Tygelin
Form: iv_infusion
Strength: 50mg/Vial
Generic Name: Tigecycline
Company: Radiant Pharmaceuticals Ltd.
MRP:৳ 600.0 (1’s Vial)
Is Antibiotic: Yes
Indications
Tygelin is used to treat infections caused by certain bacteria in the following conditions:
- Complicated Skin and Skin Structure Infections: Caused by bacteria like E. coli, Enterococcus faecalis, Staphylococcus aureus, and others.
- Complicated Intra-Abdominal Infections: Caused by bacteria like Citrobacter freundii, Klebsiella pneumoniae, Bacteroides fragilis, and others.
- Community-Acquired Bacterial Pneumonia: Caused by Streptococcus pneumoniae, Haemophilus influenzae, and Legionella pneumophila.
Pharmacology
Tygelin works by blocking protein production in bacteria, preventing them from growing. Tygelin is a type of antibiotic that is not affected by most resistance mechanisms, making Tygelin effective against a wide range of bacterial infections.
Dosage & Administration
Adults: The initial dose is 100 mg, followed by 50 mg every 12 hours. Tygelin should be given through an IV over 30 to 60 minutes.
Pediatric patients: Tygelin is not recommended for patients under 18 years old.
Geriatric patients: No major safety concerns have been noted in elderly patients.
Interaction
Tygelin may interact with medications like Digoxin and Warfarin.
Contraindications
Tygelin is not recommended for patients who are allergic to any of its ingredients.
Side Effects
The most common side effects are nausea and vomiting, usually occurring in the first 1-2 days of treatment. Other possible side effects include injection site pain, allergic reactions, chills, and more.
Pregnancy & Lactation
If you are pregnant or breastfeeding, consult your doctor before using Tygelin. Tygelin should only be used during pregnancy if necessary and if the benefits outweigh the risks.
Precautions & Warnings
Tygelin should be used with caution in people who are allergic to tetracycline antibiotics.
Overdose Effects
Overdosing may cause nausea and vomiting. There is no specific treatment for overdose, so Tygelin is important to seek medical help immediately if Tygelin occurs.
Therapeutic Class
Tygelin belongs to the Tetracycline group of drugs.
Storage Conditions
Store in a refrigerator (2-8°C) before reconstitution. Do not freeze. After reconstitution, Tygelin can be stored at room temperature for up to 24 hours or refrigerated for up to 48 hours.