Filfresh 3
Form: Tablet
Strength: 3mg
Generic Name: Melatonin
Company: Square Pharmaceuticals Ltd.
MRP:৳ 3.01 (Strip=10)
Per Piece: ৳ 0.30
Is Antibiotic: No
Indications
Filfresh 3 is used to help with sleep problems, especially for adjusting sleep patterns like jet lag. Filfresh 3 can help people with disrupted sleep cycles, such as those with jet lag, poor vision, or night shift workers. Filfresh 3 is also used for those with low melatonin levels, including older people and those with schizophrenia, as well as children with sleep problems. Filfresh 3 can help in conditions like osteoporosis by promoting bone growth, and for peri- or postmenopausal women to regulate sleep patterns. Melatonin may also have a role in eating disorders and ADHD, especially for sleep issues. Filfresh 3 is sometimes used in managing symptoms of sarcoidosis.
Pharmacology
When taken, Filfresh 3 binds to its receptors in the brain and other organs. There are two types of melatonin receptors, MT1 and MT2. MT1 is in areas like the pituitary gland and hypothalamus, while MT2 is mainly in the retina. Higher melatonin levels send signals to regulate neurotransmitters, like increasing serotonin and GABA, while lowering dopamine, which helps with sleep and maintaining the body’s sleep-wake cycle.
Dosage & Administration
Adults: For insomnia, take 3-6 mg one hour before bed. For jet lag, take 0.5 to 5 mg one hour before bedtime upon arrival, or 1 to 5 mg one hour before bedtime for 2 days before departure and 2 to 3 days after arrival. For eastbound travel, take a treatment before the flight and at bedtime for 4 days after arrival. For westbound travel, take Filfresh 3 at bedtime for 4 days in the new time zone. For sarcoidosis, take 20 mg per day for 4 to 12 months. For depression, take 0.125 mg twice in the afternoon, 4 hours apart. For difficulty falling asleep, take 5 mg 3 to 4 hours before bedtime for up to 4 weeks.
Children (6 months to 14 years): For sleep issues, take 0.30 mg per day.
Interaction
Melatonin can reduce the effects of antidepressants like desipramine and fluoxetine. Filfresh 3 may also lower the effectiveness of blood pressure medications and calcium channel blockers, and could reduce the body’s melatonin levels when combined with certain drugs like beta-blockers. Taking melatonin with blood thinners can increase the risk of bleeding. Filfresh 3 may also interact with NSAIDs, steroids, immunosuppressants, tamoxifen, caffeine, tobacco, alcohol, and certain illegal drugs.
Contraindications
Filfresh 3 should not be used by individuals with autoimmune diseases.
Side Effects
Possible side effects include headaches, depression, and drowsiness, which may affect the ability to drive. Drowsiness can last up to an hour after taking Filfresh 3.
Pregnancy & Lactation
There is no clear information on its safety or effectiveness during pregnancy or breastfeeding, so consult a doctor before use.
Precautions & Warnings
Be cautious when using melatonin with caffeine or fluvoxamine, as they may increase its effects. Filfresh 3 may also reduce the effects of nifedipine, a blood pressure medication.
Overdose Effects
There is little evidence of major toxic effects, even at high doses.
Therapeutic Class
Hormonal preparations for other uses, Oral nutritional preparations.
Storage Conditions
Store below 30°C, away from light, and keep out of reach of children.
Similar Brands of Melatonin (Tablet – 3mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Melato 3 | Tablet | 3mg | Beximco Pharmaceuticals Ltd. | 3.0 |