Amit 10
Form: tablet
Strength: 10mg
Generic Name: Amitriptyline Hydrochloride
Company: General Pharmaceuticals Ltd.
MRP:৳ 0.85 (Strip=10)
Per Piece: ৳ 0.08
Is Antibiotic: No
Indications
Amit 10 is used to treat:
- Depression, especially when sedation is needed.
- Bedwetting in children at night.
- Preventing migraines.
- Tension headaches.
- Chronic pain.
Pharmacology
The exact way Amit 10 works is not fully known, but Amit 10 is believed to stop the reabsorption of certain brain chemicals, such as norepinephrine and serotonin. These chemicals are important for mood regulation. The theory is that low levels of serotonin and norepinephrine contribute to depression, and this medicine helps by increasing their levels. Amit 10 is also unclear if its pain-relieving effects are related to improving mood or if Amit 10 works in a different way.
Dosage & Administration
Depression: Start with 75 mg daily, split into doses or take at bedtime. Increase to 150-200 mg as needed. Not recommended for children under 16.
Bedwetting in Children: For children 7-10 years old: 10-20 mg at night. For children 11-16 years old: 25-50 mg at night. Maximum treatment period is 3 months.
Migraine Prevention: 100 mg daily.
Tension Headache: 10-25 mg three times a day.
Interaction
Amit 10 can increase the sedative effects of alcohol and opioid painkillers. Using Amit 10 with Moxifloxacin or Terfenadine may increase the risk of heart problems. Certain drugs like Disulfirum and Cimetidine can affect how this medicine is broken down in the body. Using Amit 10 with diuretics (water pills) can increase the risk of low blood pressure when standing up.
Contraindications
Amit 10 should not be used if you have had a heart attack, heart rhythm problems, especially heart block, mania, or severe liver disease. Amit 10 may make you feel sedated, which could affect your ability to drive or use machines.
Side Effects
Common side effects may include:
- Excessive sweating, dry mouth, blurred vision, difficulty urinating.
- Heart problems like low blood pressure, fainting, high blood pressure, fast heart rate.
- Cognitive issues such as confusion, trouble concentrating, disorientation.
- Skin rashes, itching, sensitivity to light.
- Bone marrow issues.
- Stomach problems like nausea, loss of appetite, vomiting, diarrhea, constipation.
- Endocrine issues like swelling of testicles, breast enlargement, and unwanted milk production.
Pregnancy & Lactation
Amit 10 is classified as Pregnancy Category C. This means Amit 10 could potentially harm the baby. Use Amit 10 only if the benefit to the mother outweighs the risk. Amit 10 passes into breast milk, so consult your doctor to decide whether to stop breastfeeding or stop taking the medication, depending on which is more important for you.
Precautions & Warnings
Use caution if you have a history of epilepsy, glaucoma, urinary retention, heart disease, diabetes, liver problems, thyroid issues, or eye pressure problems. Amit 10 may worsen mania in people with certain mental health conditions.
Overdose Effects
Information not available.
Therapeutic Class
Tricyclic Antidepressant.
Storage Conditions
Store in a cool, dry place below 30°C. Keep away from light and moisture.