Besibac
Form: Eye Drop
Strength: 0.60%
Generic Name: Besifloxacin 0.6% Eye prep
Company: Popular Pharmaceuticals Ltd.
MRP:৳ 350.0 (5ml drop)
Is Antibiotic: No
Indications
Besibac is used to treat bacterial conjunctivitis (pink eye) caused by certain bacteria, including Corynebacterium pseudodiphtheriticum, Corynebacterium striatum, Haemophilus influenzae, Moraxella lacunata, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus hominis, Staphylococcus lugdunensis, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumoniae, and Streptococcus salivarius. Effectiveness for some of these bacteria was studied in a small number of cases.
Pharmacology
Besibac belongs to the fluoroquinolone class of antibiotics and works by stopping bacterial growth. Besibac does this by blocking two important bacterial enzymes: DNA gyrase and topoisomerase IV, which are needed for bacterial DNA replication and repair. Studies have shown that when used as an eye drop, very little of Besibac enters the bloodstream, keeping systemic exposure low.
Dosage & Administration
Adults & Children (1 year and older): Use one drop in the affected eye(s) three times a day for 7 days.
Pediatric Use: Not established for infants under one year. Proven effective in children one year and older.
Geriatric Use: No differences in safety and effectiveness between older and younger patients.
Interaction
No significant drug interactions have been found. This medication is for use in the eyes only.
Contraindications
Besibac should not be used by individuals who are allergic to any of its ingredients.
Side Effects
The most common side effect is redness of the eye. Other possible side effects include blurred vision, eye pain, irritation, itching, and headache, but these occur in only a small percentage of users.
Pregnancy & Lactation
There are no well-controlled studies on its use in pregnancy. Besibac may pass into breast milk, so caution is advised when used by nursing mothers.
Precautions & Warnings
Besibac is for eye use only and should not be injected into the eye. Long-term use may lead to overgrowth of non-susceptible organisms, including fungi. If a secondary infection occurs, stop using Besibac and consult a doctor. Avoid touching the dropper tip to any surface to prevent contamination. Contact lenses should not be worn during treatment. Shake well before use.
Overdose Effects
No overdose effects have been reported.
Therapeutic Class
Ophthalmic antibacterial drugs.
Storage Conditions
Store at room temperature, away from light and moisture. Do not use more than one month after opening. Shake well before each use.
Similar Brands of Besifloxacin 0.6% Eye prep (Eye Drop – 0.60%)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Besiflox | Eye Drop | 0.60% | Aristopharma Limited | 350.0 |
| Besigen | Eye Drop | 0.60% | General Pharmaceuticals Ltd. | 350.0 |
| Besixin 0.6% | Eye Drop | 0.60% | Opso Saline Ltd. | 350.0 |