Alexid
Form: Tablet
Strength: 200mg
Generic Name: Pivmecillinam
Company: Aristopharma Limited
MRP:৳ 15.0 (Tablet)
Is Antibiotic: No
Indications
Alexid is used to treat infections caused by bacteria that are sensitive to mecillinam. These include bladder infections, complicated urinary tract infections, salmonella, shigella, certain types of diarrhea, and some blood infections.
Pharmacology
Alexid is a part of a new type of penicillin called amdinopenicillin. Alexid is a prodrug, meaning Alexid turns into the active drug once absorbed in the body. Alexid works by killing bacteria by interfering with their cell wall. Alexid is especially effective against certain types of bacteria like E. coli, Salmonella, and Shigella, but not as effective against Gram-positive bacteria. Alexid doesn’t work well against Pseudomonas or Enterococcus.
Dosage & Administration
Adults: The usual dose is 1-2 tablets 3 times a day, depending on how severe the infection is. For bladder infections, take 400 mg initially, then 200 mg every 8 hours for 3 days. For chronic urinary infections, take 400 mg every 6-8 hours. For salmonella, take 1.2-2.4 gm daily for 14 days. For preventing urinary infections, take 1 tablet every evening.
Children: Children under 20 kg should take 20-60 mg/kg in 3-4 doses daily. Children over 20 kg should take the normal adult dose. For salmonella and urinary infections, the dosage is adjusted based on the child’s weight.
Interaction
There are no known interactions at this time.
Contraindications
There have been no reports of allergic reactions to Alexid in patients who are allergic to penicillin or cephalosporins. However, Alexid is better to avoid using Alexid in such patients until more information is available.
Side Effects
Alexid is usually well tolerated, even by patients with kidney problems. Some people may experience nausea, vomiting, diarrhea, or indigestion if taken on an empty stomach. Skin rashes have been reported, but more serious side effects like liver, kidney, or ear problems have not been observed. Severe allergic reactions are rare but cannot be ruled out.
Pregnancy & Lactation
If pregnant or planning to become pregnant, Alexid is better to avoid using this medicine. Alexid is found in small amounts in the umbilical cord and amniotic fluid, but Alexid is not present in breast milk.
Precautions & Warnings
Patients with kidney problems should use caution, as Alexid may cause higher drug levels in the blood. Make sure to monitor kidney function during treatment.
Overdose Effects
If an overdose occurs, symptoms may include nausea, vomiting, and stomach upset. Treatment involves managing symptoms, and if necessary, dialysis may be used to lower drug levels in the blood.
Therapeutic Class
Alexid is part of the Mecillinams class.
Storage Conditions
Store in a cool, dry place, away from light and moisture. Keep out of reach of children.
Similar Brands of Pivmecillinam (Tablet – 200mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Emcil 200 | Tablet | 200mg | Square Pharmaceuticals Ltd. | 15.05 |
| Lexipen 200 | Tablet | 200mg | EDCL | 11.66 |
| Pinam | Tablet | 200mg | Kemiko Pharmaceuticals Ltd. | 12.0 |
| Pivcilin | Tablet | 200mg | Rangs Pharmaceuticals Ltd. | 12.03 |
| Pivicil | Tablet | 200mg | General Pharmaceuticals Ltd. | 12.09 |
| Relexid | Tablet | 200mg | Renata Limited | 12.0 |