Nalbun DS
Form: Injection
Strength: 20mg/1ml
Generic Name: Nalbuphine Hydrochloride
Company: Incepta Pharmaceuticals Ltd.
MRP:৳ 100.0 (Injection)
Is Antibiotic: No
Indications
Nalbun DS is used to relieve moderate to severe pain. Nalbun DS helps with pain from heart attacks (myocardial infarction). Nalbun DS can also be used as part of anesthesia for surgery, for pain before and after surgery, and for pain relief during labor and delivery.
Pharmacology
Nalbun DS is a strong pain reliever similar to morphine. Nalbun DS works by attaching to certain receptors in the brain and body, primarily helping to relieve pain. The effect of the medicine starts in 2-3 minutes when given through an IV and in less than 15 minutes if injected into the skin or muscles. The pain relief lasts for 3 to 6 hours.
Dosage & Administration
Adult & Elderly: The usual dose is 10 mg for a 70 kg person, injected into the muscles or veins. This dose can be repeated every 3 to 6 hours if needed. The dose may be changed based on how severe the pain is and the person’s health.
For moderate to severe pain: 10-20 mg for a 70 kg person, injected into the veins or muscles, repeated if needed. Children may need up to 0.3 mg/kg body weight, repeated once or twice if needed.
For pre-surgery anesthesia: 0.1-0.2 mg/kg injected into the veins or muscles.
For pain relief during labor: 0.3-1 mg/kg injected slowly over 10-15 minutes, with maintenance doses of 0.25-0.5 mg/kg as needed.
For in-surgery pain relief: 0.25 – 0.5 mg/kg injected every 30 minutes.
For heart attack pain: 10-20 mg injected slowly, repeated after 30 minutes if necessary.
For children 18 months to 15 years old: The usual dose is 0.2 mg/kg, given through injection. The doctor will decide how often Nalbun DS should be given.
Interaction
No harmful interactions are known, but combining Nalbun DS with other opioid medications, tranquilizers, sedatives, or alcohol may increase the effect.
Contraindications
Nalbun DS should not be used by people who are allergic to Nalbuphine Hydrochloride.
Side Effects
Most people tolerate Nalbun DS well. However, some may experience side effects like drowsiness, sweating, nausea, vomiting, dizziness, dry mouth, headache, breathing problems, or asthma.
Pregnancy & Lactation
Nalbun DS is in pregnancy category B. While Nalbun DS can cross the placenta, there are no well-controlled studies. Nalbun DS should only be used during pregnancy if absolutely necessary. Nalbun DS may pass into breast milk but in very small amounts, with no significant effects. Caution is advised when giving Nalbun DS to a breastfeeding mother.
Precautions & Warnings
Nalbun DS should be used carefully in people with breathing problems, kidney or liver issues, a history of heart attacks, low blood pressure, or who have had surgery on the bile ducts.
Overdose Effects
Overdose may cause drowsiness and breathing problems. The antidote for overdose is Naloxone or Nalmefene, which can be given through an IV. Other treatments include oxygen, fluids, and medications to support blood pressure and breathing.
Therapeutic Class
Nalbun DS belongs to the class of opioid pain relievers.
Storage Conditions
Store Nalbun DS below 30°C, away from light. Keep out of the reach of children.