Renesis 70
Form: Tablet
Strength: 70mg
Generic Name: Roxadustat
Company: Beacon Pharmaceuticals Ltd.
MRP:৳ 500.0 (Strip=3)
Per Piece: ৳ 166.67
Is Antibiotic: No
Indications
Renesis 70 is used to treat adults with anemia caused by chronic kidney disease (CKD) that leads to symptoms.
Pharmacology
Renesis 70 works by blocking an enzyme called HIF-prolyl hydroxylase, which normally breaks down proteins that help regulate oxygen levels in the body. By preventing this breakdown, Renesis 70 increases the production of erythropoietin, a hormone that boosts red blood cell production. Renesis 70 also helps improve iron availability and boosts hemoglobin (Hb) levels, supporting better blood oxygen levels. This medication also helps manage iron levels in CKD patients, increasing iron absorption and release while lowering cholesterol levels.
Dosage & Administration
Adults: Renesis 70 should be taken orally three times per week, not on consecutive days. The starting dose is 50 mg for patients not on other anemia treatments. For patients under 100 kg, the dose is 70 mg, and for those 100 kg or more, Renesis 70 is 100 mg. If switching from other treatments, the starting dose is 70 or 100 mg.
Adjustments: The dose may be increased or decreased based on the patient’s response. If the hemoglobin level rises too quickly, the dose should be reduced or treatment stopped. If a dose is missed, take Renesis 70 as soon as possible if there’s enough time before the next dose. Do not take two doses at once.
Method: The tablets can be taken with or without food.
Interaction
Renesis 70 may interact with phosphate binders and other products containing multivalent cations, reducing its effectiveness. Renesis 70 may also increase the levels of other medications like gemfibrozil, probenecid, and certain statins. Always consult a doctor before using Renesis 70 with other medications.
Contraindications
There are no specific contraindications for this medication.
Side Effects
Common side effects include high blood pressure, blood clots, diarrhea, swelling in the legs, high potassium levels, and nausea.
Pregnancy & Lactation
This medication should not be used if pregnant or breastfeeding. Always consult a doctor before use during pregnancy.
Precautions & Warnings
Renesis 70 should be used cautiously in people at risk of blood clots, especially those with a history of clots or obesity. Renesis 70 should also be avoided in patients with serious infections or liver problems. Pregnant women should not take this medication.
Overdose Effects
Overdose symptoms may include a fast heart rate and higher than necessary hemoglobin levels. If overdosed, treatment may involve reducing or stopping the medication.
Therapeutic Class
Renesis 70 belongs to the class of medications used to treat anemia associated with kidney disease.
Storage Conditions
Store in a cool, dry place, away from light, and out of reach of children.
Similar Brands of Roxadustat (Tablet – 70mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Oroxat 70 | Tablet | 70mg | Eskayef Pharmaceuticals Ltd. | 400.0 |
| Renofix 70 | Tablet | 70mg | Everest Pharmaceuticals Ltd. | 500.0 |