Medroxy 5
Form: Tablet
Strength: 5mg
Generic Name: Medroxyprogesterone Acetate
Company: Popular Pharmaceuticals Ltd.
MRP:৳ 5.4 (Strip=15)
Per Piece: ৳ 0.36
Is Antibiotic: No
Indications
Medroxy 5 is used to treat secondary amenorrhea (absence of menstruation) and abnormal uterine bleeding caused by hormonal imbalance, as long as there are no underlying conditions like fibroids or uterine cancer. Medroxy 5 is also used to reduce the risk of endometrial hyperplasia in postmenopausal women who are taking daily oral estrogen supplements.
Pharmacology
Medroxy 5 works by transforming the lining of the uterus into a secretory state when given in recommended doses. Medroxy 5 has androgenic and anabolic effects but does not have significant estrogenic activity. When given by injection, Medroxy 5 prevents ovulation by stopping the production of hormones that trigger follicle development. However, this effect is not seen with the usual oral dosage.
Dosage & Administration
Secondary Amenorrhea: Take 5 to 10 mg daily for 5 to 10 days. For the best results, take 10 mg daily for 10 days. You can start this therapy at any time, and withdrawal bleeding usually happens within 3 to 7 days after stopping the medication.
Abnormal Uterine Bleeding Due to Hormonal Imbalance: Start taking 5 to 10 mg daily for 5 to 10 days, starting on day 16 or 21 of your menstrual cycle. Withdrawal bleeding usually happens within 3 to 7 days after stopping the therapy.
Endometrial Hyperplasia Prevention: For postmenopausal women taking estrogen, 5 to 10 mg daily for 12 to 14 days a month can help reduce the risk of endometrial hyperplasia. This therapy can start on either day 1 or day 16 of the cycle.
Interaction
There are no known interactions for this medication.
Contraindications
Medroxy 5 should not be used by women who have abnormal genital bleeding, breast cancer, estrogen- or progesterone-dependent tumors, blood clots, or certain heart conditions. Medroxy 5 is also not recommended for those with liver disease or pregnancy.
Side Effects
Common side effects may include abnormal uterine bleeding, breast tenderness, gastrointestinal issues like nausea, skin reactions like rash, and central nervous system issues like dizziness and headache. Serious effects may include blood clots and eye problems like retinal thrombosis.
Pregnancy & Lactation
Medroxy 5 should not be used during pregnancy, especially during the first trimester, as Medroxy 5 may increase the risk of certain birth defects. Medroxy 5 should also be avoided during breastfeeding, as Medroxy 5 passes into breast milk.
Precautions & Warnings
Women who have not had a hysterectomy should take precautions, as there is a risk of endometrial hyperplasia. Other conditions that require caution include high blood pressure, liver issues, and fluid retention. Regular monitoring is advised in these cases. Medroxy 5 may also worsen conditions like asthma, diabetes, and migraines.
Overdose Effects
Overdose may cause nausea, vomiting, dizziness, abdominal pain, and fatigue. Treatment involves stopping the medication and providing supportive care.
Therapeutic Class
Medroxy 5 belongs to the class of Female Sex Hormones.
Storage Conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.
Similar Brands of Medroxyprogesterone Acetate (Tablet – 5mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Medrina | Tablet | 5mg | Beacon Pharmaceuticals Ltd. | 4.7 |
| Medrogest 5 | Tablet | 5mg | Renata Limited | 5.38 |
| Mepogest 5 | Tablet | 5mg | Drug International Ltd. | 5.5 |
| Perlutex | Tablet | 5mg | Leo Pharmaceutical Products, Denmark | 10.62 |
| Provenor | Tablet | 5mg | Eskayef Pharmaceuticals Ltd. | 5.0 |