Ecovit 400
Form: Capsule
Strength: 400mg
Generic Name: Vitamin E (Alpha-tocopherol)
Company: Globe Pharmaceuticals Ltd.
MRP:৳ 6.0 (Strip=10)
Per Piece: ৳ 0.60
Is Antibiotic: No
Indications
Ecovit 400 is used to treat and prevent vitamin E deficiency. Ecovit 400 is also suggested as an antioxidant to help with various health conditions such as:
- Alzheimer’s Disease
- Rheumatoid Arthritis Pain
- Nerve Damage caused by Chemotherapy
- Male Infertility
- Age-related Macular Degeneration
- Keratectomy
- Premenstrual Syndrome
- Painful Menstrual Periods
- Heart Disease (to improve the effectiveness of nitrates)
Pharmacology
Ecovit 400 acts as an antioxidant in the body, protecting polyunsaturated fatty acids and other oxygen-sensitive substances like vitamin A and C from damage. In premature babies, a lack of vitamin E can cause irritability, swelling, blood clots, and anemia. Adults and children with low vitamin E levels may experience muscle weakness, short red blood cell survival, and increased damage from oxidation.
Dosage & Administration
For Age-related Macular Degeneration: 400-600 IU daily.
For Heart Disease (to improve effectiveness of Nitrates): 200 IU three times daily.
For Dementia/Alzheimer’s Disease: 800-2000 IU one to two times daily.
For Rheumatoid Arthritis Pain: 600 IU daily.
For Male Infertility: 200-600 IU daily.
For Menstrual Syndrome: 400 IU daily.
For Painful Menstrual Periods: 200 IU daily.
Interaction
Ecovit 400 may reduce the absorption of Vitamin A and affect the function of Vitamin K. Ecovit 400 can also increase the effects of the blood thinner Warfarin.
Contraindications
Ecovit 400 is contraindicated for people with a known allergy to vitamin E or related components. Those with rare inherited problems like fructose intolerance, glucose-galactose malabsorption, or sucrose-isomaltase insufficiency should not take this medicine.
Side Effects
Side effects are rare but may include diarrhea and stomach pain if taking more than 1000 IU daily.
Pregnancy & Lactation
There is no evidence about the safety of high doses of vitamin E during pregnancy, so Ecovit 400 is best avoided, especially in the first trimester. There is no information about whether Ecovit 400 passes into breast milk, so Ecovit 400 is advised not to use Ecovit 400 during lactation.
Precautions & Warnings
Ecovit 400 may increase bleeding in people with vitamin K deficiency or those taking blood thinners. Ecovit 400’s important to monitor blood clotting levels (prothrombin time and INR). Ecovit 400 may also increase the risk of blood clots in patients who are prone to thrombosis, especially women taking estrogen-based contraceptives.
Overdose Effects
Overdosing may cause temporary stomach issues. If necessary, general supportive measures should be used.
Therapeutic Class
Herbal and Nutraceuticals, Vitamin-E Preparations
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
Similar Brands of Vitamin E (Alpha-tocopherol) (Capsule – 400mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| E-Cap 400 | Capsule | 400mg | Drug International Ltd. | 7.0 |
| E-Fill | Capsule | 400mg | General Pharmaceuticals Ltd. | 6.0 |
| E-Gel Ds 400 | Capsule | 400mg | Renata Limited | 6.0 |
| E-Soft 400 | Capsule | 400mg | Pacific Pharmaceuticals Ltd. | 6.0 |
| Evitacap 400 | Capsule | 400mg | Ziska Pharmaceuticals Ltd. | 7.0 |
| Lifil-E 400 | Capsule | 400mg | The ACME Laboratories Ltd. | 6.5 |
| Nature-E 400 | Capsule | 400mg | Unimed Unihealth Pharmaceuticals Ltd. | 7.0 |
| Ovit-E 400 | Capsule | 400mg | Opsonin Pharma Limited | 6.02 |
| Vegecap-E | Capsule | 400mg | NIPRO JMI Pharma Limited | 7.02 |