Ximetil IV/IM
Form: Injection
Strength: 750mg/vial
Generic Name: Cefuroxime
Company: Globe Pharmaceuticals Ltd.
MRP:৳ 125.0 (Injection)
Is Antibiotic: Yes
Indications
Ximetil IV/IM is used to treat infections caused by bacteria that are sensitive to Ximetil IV/IM. This includes conditions like:
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes.
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase producing strains), or Streptococcus pyogenes.
Pharmacology
Ximetil IV/IM contains Cefuroxime, a second-generation antibiotic that kills bacteria by preventing them from making their cell walls. Ximetil IV/IM works against a wide range of Gram-positive and Gram-negative bacteria, including those that produce beta-lactamase.
Ximetil IV/IM also contains Clavulanic acid, which blocks beta-lactamase enzymes. This helps protect Cefuroxime from being broken down, making Ximetil IV/IM more effective in treating infections caused by bacteria resistant to some antibiotics.
Dosage & Administration
Adolescents and adults (13 years and older):
- Pharyngitis/tonsillitis: 250 mg twice a day for 5-10 days
- Acute bacterial maxillary sinusitis: 250 mg twice a day for 10 days
- Acute bacterial exacerbation of chronic bronchitis: 250-500 mg twice a day for 10 days
- Secondary bacterial infections of acute bronchitis: 250-500 mg twice a day for 5-10 days
- Uncomplicated skin infections: 250-500 mg twice a day for 10 days
- Uncomplicated urinary tract infections: 250 mg twice a day for 7-10 days
- Uncomplicated Gonorrhoea: 1000 mg twice a day, single dose
- Community acquired pneumonia: 250-500 mg twice a day for 5-10 days
- MDR Typhoid Fever: 500 mg twice a day for 10-14 days
- Early Lyme disease: 500 mg twice a day for 20 days
Pediatric patients (3 months to 12 years):
- Pharyngitis/Tonsillitis: 20 mg/kg/day twice a day for 5-10 days
- Acute otitis media: 30 mg/kg/day twice a day for 10 days
- Acute bacterial maxillary sinusitis: 30 mg/kg/day twice a day for 10 days
- Impetigo: 30 mg/kg/day twice a day for 10 days
Ximetil IV/IM can be taken with or without food.
Interaction
If taken with probenecid, Ximetil IV/IM increases the amount of the medicine in your body. Medicines that reduce stomach acidity may make Ximetil IV/IM less effective by reducing its absorption.
Contraindications
Ximetil IV/IM should not be taken by people who are allergic to cephalosporins or have Pseudomembranous Colitis.
Side Effects
Generally, Ximetil IV/IM is well tolerated. Some common side effects may include nausea, vomiting, diarrhea, and stomach pain. Prolonged use may cause the growth of resistant microorganisms. In rare cases (<0.2%), Ximetil IV/IM may cause kidney problems, severe allergic reactions, swelling, rashes, or other serious effects.
Pregnancy & Lactation
Ximetil IV/IM should be avoided during the first trimester if possible. However, Ximetil IV/IM can be safely used during later stages of pregnancy to treat infections. Ximetil IV/IM can pass into breast milk in small amounts, so caution is needed when nursing.
Precautions & Warnings
Ximetil IV/IM should be used carefully in patients who are taking strong diuretics or have a history of colitis.
Overdose Effects
No information available.
Therapeutic Class
Second-generation Cephalosporins, Vaccines, Anti-sera & Immunoglobulins.
Storage Conditions
Store in a cool, dry place (below 30°C), away from light and moisture. Keep out of reach of children.
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