Aciflox 200 is a broad-spectrum antibiotic that works by inhibiting DNA gyrase and topoisomerase IV, which are enzymes necessary for bacterial survival. This action helps Aciflox 200 kill various bacteria that infect the lungs and airways. Aciflox 200 has been proven effective in many clinical trials for treating bacterial infections and is stronger in some cases compared to other antibiotics like fluoroquinolones. Aciflox 200 works well against gram-positive bacteria like Streptococcus pneumoniae, Staphylococcus aureus, Mycobacteria, and Chlamydia species.

Absorption: Aciflox 200 is well absorbed when taken orally, with a bioavailability of 92%. After taking a 400-mg dose, the peak plasma concentration is reached within 3 to 6 hours. Taking Aciflox 200 with food or milk does not affect how well Aciflox 200 is absorbed, but taking Aciflox 200 with antacids can reduce absorption by up to 50%.

Distribution: Once in the bloodstream, Aciflox 200 spreads well throughout the body and reaches high concentrations in respiratory tissues. Aciflox 200 accumulates in the lungs, where its concentration is 3 to 6 times higher than in the plasma.

Metabolism: Aciflox 200 is processed by the liver and does not interfere with other drugs that are broken down by the liver’s cytochrome system.

Excretion: Aciflox 200 is eliminated equally in the feces and urine, with about 10% of the drug being excreted unchanged in the urine for people with normal kidney function.