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Acos 250

Form: Capsule

Strength: 250mg

Generic Name: Azithromycin

Company: Radiant Pharmaceuticals Ltd.

MRP:৳ 30.0   (Box=6)

Per Piece: ৳ 5.00  

Is Antibiotic: Yes

Indications

Acos 250 is used to treat bacterial eye infections caused by certain bacteria like CDC coryneform group G, Haemophilus influenzae, Staphylococcus aureus, Streptococcus mitis group, and Streptococcus pneumonia.

Pharmacology

Acos 250 is stable in acid and can be taken orally without needing protection from stomach acid. Acos 250 is absorbed easily, especially when taken on an empty stomach. After taking Acos 250, the highest level in the body is reached in 2.1 to 3.2 hours. Acos 250 is concentrated in the white blood cells and is delivered to the infection site. The drug is stored in the tissues and released over time, with levels in tissues being over 50 times higher than in the blood. This allows a single dose to remain effective for several days. After one dose, Acos 250 stays in the body for up to 68 hours. Acos 250 is mainly eliminated through bile, with a small amount leaving the body unchanged in urine.

Microbiology

Acos 250 works by binding to a part of bacteria, stopping them from making proteins, which prevents the bacteria from growing. Acos 250 does not affect the bacteria’s genetic material. Acos 250 is effective against many bacteria, including:

  • Gram-positive bacteria like Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes.
  • Gram-negative bacteria like Haemophilus influenzae, Neisseria gonorrhoeae, and Moraxella catarrhalis.
  • Other bacteria like Chlamydia pneumoniae, Mycoplasma pneumoniae, and Chlamydia trachomatis.

Acos 250 works even against some bacteria that produce betalactamase, an enzyme that makes other antibiotics less effective.

Dosage & Administration

Adults and children 1 year and older: Put 1 drop in the affected eye(s) twice a day for the first 2 days, then once a day for the next 5 days.

Pediatric use: Acos 250 has not been tested in children under 1 year of age, so Acos 250 is not recommended for them.

Interaction

No interaction studies have been done with Azithromycin Eye Drops.

Contraindications

Acos 250 should not be used by anyone who is allergic to any of its ingredients.

Side Effects

Possible side effects include eye irritation, skin irritation, corneal damage, dry eyes, and inflammation of the cornea.

Pregnancy & Lactation

Acos 250 is classified as Pregnancy Category B, meaning no harm was found in animal studies. However, Acos 250 should only be used during pregnancy if absolutely necessary. Acos 250 is not known if Acos 250 passes into breast milk, so caution is advised when using Acos 250 while nursing.

Precautions & Warnings

Acos 250 is only for use in the eyes. Acos 250 should not be used in the bloodstream, injected into the eye, or placed into the inner part of the eye.

Overdose Effects

No specific overdose effects have been reported.

Therapeutic Class

Acos 250 belongs to the Macrolide class of antibiotics.

Storage Conditions

Store the unopened bottle in the fridge between 2°C to 8°C. After opening, keep Acos 250 at room temperature (25°C) for up to 14 days. Discard Acos 250 after 14 days.

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