Acryth
Form: Powder for Suspension
Strength: 125mg/5ml
Generic Name: Erythromycin
Company: Monicopharma Limited
MRP:৳ 60.0 (100ml bot)
Is Antibiotic: Yes
Indications
Acryth is used to treat a wide range of infections. These include:
- Upper respiratory infections like sore throat, tonsil abscess, and sinus infections.
- Lower respiratory infections such as bronchitis.
- Ear infections like middle ear infection, outer ear infection, and mastoiditis.
- Eye infections such as eyelid inflammation and certain types of eye infections.
- Skin and soft tissue infections like boils, impetigo, and cellulitis.
- Gastrointestinal infections such as gallbladder infection and some stomach infections.
- Preventive use in surgery, trauma, burns, and rheumatic fever.
- Other infections like bone infection, diphtheria, scarlet fever, and whooping cough.
Pharmacology
Acryth works by stopping protein production in bacteria, specifically by targeting certain parts of their ribosomes. Acryth is effective against many types of bacteria, including some that cause respiratory and skin infections, as well as mycoplasma and chlamydia bacteria.
Absorption: Acryth is absorbed better when taken with food, and its absorption can be affected by the presence of food in the stomach.
Blood concentration: After taking a 500 mg dose, peak levels are reached in 1 to 4 hours. The drug stays in the bloodstream for about 1 to 4 hours.
Distribution: Acryth spreads widely in body tissues and fluids, especially in the liver and spleen. Acryth can cross into the cerebrospinal fluid during infections of the brain lining and also passes through the placenta and is found in breast milk.
Excretion: A small portion of Acryth is excreted through urine, and the majority is eliminated through the bile.
Dosage & Administration
Adults and Children over 8 years: 250-500 mg every six hours for mild to moderate infections, which can be increased up to 4 grams a day for severe cases.
Elderly: No special dosage recommendations. Acryth can be taken three times or twice a day, dividing the total daily dose into equal parts.
Children aged 2 to 8 years: 250 mg every six hours or 30-50 mg/kg body weight per day divided into four equal doses.
Infants and Children up to 2 years: 500 mg divided into doses or 30-50 mg/kg body weight divided into doses.
Interaction
When taken with high doses of theophylline, Acryth can increase the level of theophylline in the blood, which can lead to toxicity. In such cases, the dose of theophylline should be reduced.
Contraindications
Acryth is not recommended for people who are allergic to Acryth.
Side Effects
Allergic reactions are rare and usually mild, though severe reactions like anaphylaxis can occur. Some people may experience stomach upset, nausea, and vomiting, but this usually improves over time without changing the dosage.
Pregnancy & Lactation
Studies have not shown harm to unborn babies, but caution should be used when prescribing Acryth to pregnant or breastfeeding women, as Acryth can cross the placenta and appear in breast milk.
Precautions & Warnings
Acryth should be used carefully in people with liver problems since Acryth is mainly removed from the body through the bile.
Overdose Effects
If an overdose occurs, the medicine should be stopped. Measures should be taken to remove any unabsorbed drug, and other treatments should be provided as needed. Acryth cannot be removed by dialysis.
Therapeutic Class
Anti-diarrheal, Antimicrobial drugs, Macrolides.
Storage Conditions
Store below 25°C, away from light and moisture. Keep out of the reach of children.
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