Acuren 50
Form: Tablet
Strength: 50mg
Generic Name: Hydrochlorothiazide
Company: Incepta Pharmaceuticals Ltd.
MRP:৳ 1.0 (Box=100)
Per Piece: ৳ 0.01
Is Antibiotic: No
Indications
Acuren 50 is used to treat swelling caused by heart failure, liver cirrhosis, premenstrual tension, and kidney problems like nephrotic syndrome, glomerulonephritis, or chronic kidney failure. Acuren 50 is also used for high blood pressure, either on its own or with other blood pressure-lowering medications.
Pharmacology
Acuren 50 is a type of diuretic (water pill) that helps the body get rid of excess fluid. Acuren 50 works by blocking the reabsorption of sodium and chloride in the kidneys, causing the body to lose water. This can also lead to lower potassium levels and increased uric acid in the blood. While Acuren 50 helps lower blood pressure, its exact mechanism is not fully understood, but Acuren 50 works by relaxing blood vessels. Acuren 50 also prevents complications related to high blood pressure.
Dosage & Administration
For Edema: Start with 25 to 50 mg per day. The dose may be reduced for long-term use. The maximum daily dose is 100 mg.
For Hypertension: Start with 25 mg per day. Acuren 50 may be increased to 50 mg per day if needed.
For Elderly: In some elderly patients, an initial dose of 12.5 mg per day may be enough.
For Children: Children usually start with 1 to 2 mg per kg of body weight in two divided doses. Infants under 6 months may need up to 3 mg per kg daily.
Interaction
Taking alcohol, barbiturates, or narcotics with Acuren 50 may cause low blood pressure. Acuren 50 may also require changes in the dose of certain diabetes medications. Other blood pressure-lowering drugs may have a stronger effect when taken together. When starting an ACE inhibitor, diuretic therapy should be stopped 2-3 days before to avoid sudden drops in blood pressure. Cholestyramine and colestipol resins can reduce how much of Acuren 50 is absorbed. Other medications, like steroids, muscle relaxants, or NSAIDs, may also interact with Acuren 50.
Contraindications
Acuren 50 is not suitable for people with anuria (lack of urine), severe kidney or liver problems, Addison’s disease, high calcium levels, or who are taking lithium.
Side Effects
Common side effects include stomach upset, nausea, vomiting, diarrhea, constipation, dizziness, headache, and skin reactions like rash. More serious effects can include low blood pressure, blood disorders, and allergic reactions. Acuren 50 may also cause high blood sugar, electrolyte imbalances, and kidney problems. If side effects are severe, treatment should be stopped or the dose reduced.
Pregnancy & Lactation
If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using Acuren 50. During pregnancy, Acuren 50 should only be used if absolutely necessary, as Acuren 50 can cause harm to the baby. Acuren 50 passes into breast milk, so breastfeeding should be avoided if the drug is necessary.
Precautions & Warnings
Acuren 50 is important to monitor for signs of fluid and electrolyte imbalance, such as thirst, weakness, confusion, and muscle cramps. Severe potassium loss may affect heart function. In some cases, this drug can worsen kidney and liver problems. Acuren 50 may also cause high levels of uric acid, leading to gout. People with diabetes, high cholesterol, or lupus should use Acuren 50 with caution. Thiazides may also affect calcium and thyroid levels, and Acuren 50 should be stopped before tests for parathyroid function.
Overdose Effects
Overdose symptoms often involve electrolyte imbalances and dehydration, which can cause low blood pressure, heart problems, and confusion. In case of overdose, immediate medical attention is needed. Treatments may include induced vomiting, gastric lavage, and rehydration. In severe cases, oxygen or artificial respiration may be required.
Therapeutic Class
Acuren 50 belongs to the class of thiazide diuretics and related drugs.
Storage Conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.
Similar Brands of Hydrochlorothiazide (Tablet – 50mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Hypezide | Tablet | 50mg | Pacific Pharmaceuticals Ltd. | 1.0 |