Adinir
Form: Powder for Suspension
Strength: 125mg/5ml
Generic Name: Cefdinir
Company: The ACME Laboratories Ltd.
MRP:৳ 175.66 (60ml bot)
Is Antibiotic: Yes
Indications
Adinir is used to treat the following conditions:
- Community Acquired Pneumonia
- Acute Exacerbations of Chronic Bronchitis
- Acute Maxillary Sinusitis
- Pharyngitis/Tonsillitis
- Acute Bacterial Otitis Media
- Uncomplicated Skin and Skin Structure Infections
Pharmacology
Adinir is a semisynthetic third-generation oral cephalosporin antibiotic. Adinir works by killing bacteria and is effective against a wide range of common bacteria, including those that produce beta-lactamase. These include Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella pneumoniae, and Proteus mirabilis. Like other cephalosporins, Adinir kills bacteria by preventing them from forming their cell wall.
Dosage & Administration
Adult Dosing: The total daily dose for all infections is 600 mg. The dosage schedule is as follows:
| Type of Infection | Dosage | Duration |
|---|---|---|
| Acute Exacerbations of Chronic Bronchitis | 300 mg twice daily or 600 mg once daily | 5 to 10 days |
| Pharyngitis/Tonsillitis | 300 mg twice daily or 600 mg once daily | 10 days |
| Acute Bacterial Otitis Media | 300 mg twice daily or 600 mg once daily | 10 days |
| Acute Maxillary Sinusitis | 300 mg twice daily or 600 mg once daily | 10 days |
| Community Acquired Pneumonia | 300 mg twice daily | 10 days |
| Uncomplicated Skin and Skin Structure Infections | 300 mg twice daily or 600 mg once daily | 10 days |
Pediatric Dosing (Powder for Oral Suspension): The total daily dose is 14 mg/kg of body weight, up to a maximum of 600 mg per day. The dosing schedule is as follows:
| Type of Infection | Dosage | Duration |
|---|---|---|
| Acute Bacterial Otitis Media | 7 mg/kg twice daily or 14 mg/kg once daily | 5 to 10 days |
| Pharyngitis/Tonsillitis | 7 mg/kg twice daily or 14 mg/kg once daily | 10 days |
| Acute Maxillary Sinusitis | 7 mg/kg twice daily or 14 mg/kg once daily | 10 days |
| Uncomplicated Skin and Skin Structure Infections | 7 mg/kg twice daily | 10 days |
Reconstitution of Powder for Suspension: Shake the bottle well to ensure the powder does not clog. Add 40 ml (8 x 5 ml spoonfuls) of boiled and cooled water using the provided 5 ml spoon. Shake well until the powder is completely mixed. Use the reconstituted suspension within 10 days if stored at room temperature or 14 days if refrigerated. Shake well before each use.
Interaction
Adinir should not be taken with antacids or iron supplements within two hours, as they may reduce its effectiveness. Probenecid, a medication used for gout, may slow down the elimination of Adinir from the body.
Contraindications
Adinir should not be used by patients who are allergic to cephalosporin antibiotics.
Side Effects
Common side effects include diarrhea, vaginal yeast infections, nausea and vomiting, headache, and rash.
Pregnancy & Lactation
Adinir is categorized as pregnancy category B. However, there are no well-controlled studies in pregnant women, so Adinir should only be used during pregnancy if absolutely necessary. Adinir is not detected in breast milk after taking a 600 mg dose.
Precautions & Warnings
Adinir should be used with caution in individuals with a history of colitis (inflammation of the colon). If a patient has kidney issues, the daily dose should be adjusted.
Overdose Effects
No specific overdose effects are known.
Therapeutic Class
Adinir belongs to the third-generation cephalosporins class of antibiotics.
Storage Conditions
Store at room temperature, away from light. After mixing, the suspension can be used within 7 days if stored at room temperature or within 14 days if kept in a refrigerator (2-8°C). Always keep the bottle tightly closed.
Similar Brands of Cefdinir (Powder for Suspension – 125mg/5ml)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Cefexta | Powder for Suspension | 125mg/5ml | Unimed Unihealth Pharmaceuticals Ltd. | 225.0 |
| Cefida | Powder for Suspension | 125mg/5ml | Beximco Pharmaceuticals Ltd. | 176.0 |
| Cefinir | Powder for Suspension | 125mg/5ml | Aristopharma Limited | 0.0 |
| Palcef | Powder for Suspension | 125mg/5ml | Renata Limited | 175.0 |
| Ridicef | Powder for Suspension | 125mg/5ml | Navana Pharmaceuticals Ltd. | 175.65 |