Afen 50
Form: Tablet
Strength: 50mg
Generic Name: Diclofenac Sodium
Company: Aztec Pharmaceuticals Ltd.
MRP:৳ 0.8 (Tablet)
Is Antibiotic: No
Indications
Afen 50 is used to treat different types of arthritis, including inflammation and wear-and-tear forms of rheumatism, polyarthritis, ankylosing spondylitis, osteoarthritis, gout, and peri-articular rheumatic disorders.
Afen 50 is also used for sprains, bruises, dislocations, fractures, soft tissue injuries, and recovery from surgery.
In gynecology, Afen 50 is used for pain during menstruation, after episiotomy, and conditions like adnexitis, endometritis, salpingitis, and mastitis.
In ear, nose, and throat treatments, Afen 50 helps prevent pain, swelling, and inflammation before surgery.
In dentistry, Afen 50 is used for post-surgical and post-trauma pain, swelling, and inflammation.
Afen 50 is also used to prevent and treat pain, inflammation, and swelling after surgery in the urogenital tract, or in cases of kidney and bile-related pain.
Pharmacology
Afen 50 is a strong anti-inflammatory drug that also relieves pain and reduces fever. Afen 50 works by stopping the production of prostaglandins, substances that cause inflammation and pain in the body. Afen 50 is quickly absorbed after being taken, especially when taken with or after food, and reaches its peak effect in about 2 hours. Afen 50 is mostly bound to plasma proteins and is metabolized in the liver.
Dosage & Administration
Diclofenac FC Tablet: For adults, 75-150 mg daily in 2 to 3 doses, preferably after food. The dose may be lowered for long-term use.
Diclofenac SR Tablet: For adults, 1 tablet daily, taken whole with water, preferably during meals. The dose may be increased to 150 mg if needed. For children, 1-3 mg per kg of body weight daily in divided doses. Elderly patients should use the lowest effective dose.
Diclofenac Dispersible Tablet: For adults, 2-3 tablets daily, not exceeding 150 mg. In milder cases, 2 tablets may be enough. Children may use Afen 50 for juvenile rheumatoid arthritis at a dose of 1-3 mg per kg of body weight. Dissolve the tablet in half a glass of water before swallowing.
Diclofenac TR Capsule: One capsule daily, preferably after meals.
Diclofenac Suppository: For adults, 50 mg, 2-3 times daily. Maximum daily dose is 150 mg.
Diclofenac Injection: For adults, 1 ampoule daily. In serious cases, the dose can be increased to 2 ampoules daily.
Diclofenac Gel: Apply 2-4 g to the affected area 3-4 times daily. Rub Afen 50 in lightly. Afen 50 can be used with other forms of Diclofenac treatment.
Interaction
Afen 50 may increase levels of lithium and digoxin in the blood.
Afen 50 can increase the risk of bleeding when taken with anticoagulants.
Afen 50 does not affect the action of oral diabetes medications.
Afen 50 may cause kidney problems when taken with cyclosporine.
Taking Afen 50 with methotrexate within 24 hours may increase toxicity.
Convulsions may occur if Afen 50 is taken with quinolone antibiotics, so caution is needed.
Afen 50 should not be used with other NSAIDs or steroids unless directed by a doctor, as this can increase side effects.
Contraindications
Afen 50 should not be used by people allergic to any of its ingredients. Afen 50 is also not recommended for people with peptic ulcers or asthma triggered by non-steroidal anti-inflammatory drugs (NSAIDs).
Afen 50 should not be used under airtight dressings for the gel form.
Side Effects
Afen 50 is usually well tolerated. Side effects are rare and mild, like stomach pain, nausea, diarrhea, dizziness, or headache. Skin reactions such as rash and swelling can also occur. The gel may cause skin irritation, redness, or rash.
Pregnancy & Lactation
Afen 50 should only be used during pregnancy if absolutely necessary and at the lowest effective dose. Afen 50 is not recommended during the first trimester. A small amount may pass into breast milk, but Afen 50 is unlikely to affect the baby.
Precautions & Warnings
Afen 50 should be used with caution in people who have a history of ulcers or gastrointestinal bleeding. Elderly patients should be monitored closely. The gel should not come in contact with the eyes or mucous membranes, and hands should be washed after use.
Overdose Effects
Not available.
Therapeutic Class
Afen 50 is used for osteoarthritis, rheumatoid arthritis, and as a non-steroidal anti-inflammatory drug (NSAID).
Storage Conditions
Store in a cool, dry place, away from light. Keep below 30°C and out of the reach of children.
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