Afrin 0.025%
Form: Nasal Drops
Strength: 0.025%
Generic Name: Oxymetazoline Hydrochloride .025 % Nasal prep
Company: Aristopharma Limited
MRP:৳ 65.0 (10ml drop)
Is Antibiotic: No
Indications
Afrin 0.025% is used to treat nasal congestion caused by conditions like acute or chronic rhinitis, common cold, sinusitis, upper respiratory allergies, nosebleeds, and hay fever. Afrin 0.025% is also used as a nasal decongestant in middle ear infections.
Pharmacology
Afrin 0.025% is an imidazoline derivative and works as a sympathomimetic amine. Afrin 0.025% directly affects α-adrenoceptors but has no effect on β-adrenoceptors. When applied to the nasal passages, Afrin 0.025% rapidly and effectively narrows blood vessels, reducing swelling in the nasal mucosa. This improves airflow and helps clear the nasal sinuses.
Dosage & Administration
Oxymetazoline Nasal Spray:
Adults and children (6 years and older): 2 or 3 sprays in each nostril, twice daily for 3-5 days.
Elderly: No dosage adjustment needed for nasal administration.
Children under 6 years: Not recommended for children under 6 years old.
Oxymetazoline Nasal Drops:
Adults and children (6 years and older): 2-3 drops of 0.05% nasal drops in each nostril twice daily.
Children (2-5 years): 2-3 drops of 0.025% nasal drops in each nostril twice daily.
Interaction
Afrin 0.025% should not be used with MAO inhibitors or within 14 days after stopping such treatment.
Contraindications
Afrin 0.025% is contraindicated in patients with heart disease, hyperthyroidism, prostate problems, angle-closure glaucoma, or allergies to any of its ingredients.
Side Effects
Common side effects include local irritation and dryness in the mouth and throat. Temporary discomfort such as burning, stinging, sneezing, or an increase in nasal discharge may also occur.
Pregnancy & Lactation
The safety of this nasal spray during pregnancy and breastfeeding has not been fully established, but Afrin 0.025% is not considered to pose a significant risk during these periods.
Precautions & Warnings
Keep Afrin 0.025% away from the eyes. Do not use the spray for more than seven days without consulting a doctor. Frequent or long-term use may cause the nasal congestion to come back or worsen.
Overdose Effects
Overdose may cause local irritation and rebound congestion. Treatment is usually symptomatic and aimed at relieving the symptoms.
Therapeutic Class
Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations.
Storage Conditions
Store below 30°C in a dry place, away from light. Do not refrigerate or freeze. Keep out of the reach of children.
Similar Brands of Oxymetazoline Hydrochloride .025 % Nasal prep (Nasal Drops – 0.025%)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Zoli 0.025% | Nasal Drops | 0.025% | Healthcare Pharmaceuticals Ltd. | 40.0 |