Amipride 50
Form: Tablet
Strength: 50mg
Generic Name: Amisulpride
Company: Beacon Pharmaceuticals Ltd.
MRP:৳ 20.0 (Strip=10)
Per Piece: ৳ 2.00
Is Antibiotic: No
Indications
Amipride 50 is used to treat both acute and long-term schizophrenia. This includes people with symptoms like delusions, hallucinations, and disorganized thoughts, as well as those with more emotional and social withdrawal symptoms.
Pharmacology
Amipride 50 is an antipsychotic medication that helps manage schizophrenia symptoms. Amipride 50 works by binding to certain dopamine receptors in the brain. Unlike many other similar drugs, Amipride 50 doesn’t affect other receptors like serotonin or histamine much. Amipride 50 also doesn’t cause severe side effects like other drugs in its class.
Dosage & Administration
Oral dose: For acute psychosis, the usual dose is between 400 mg and 800 mg per day. In some cases, this can be increased to 1200 mg per day, but higher doses don’t offer extra benefits and can cause more side effects. Doses should be adjusted based on how the patient responds. Amipride 50 is best taken before meals.
Injectable dose: For preventing or treating nausea after surgery, 5 mg is given intravenously for prevention, and 10 mg for treatment.
Interaction
Alcohol can increase side effects like drowsiness and confusion when taken with this medicine. Amipride 50 may also interact with drugs like Diltiazem, Pregabalin, and Tramadol, as well as other antipsychotic drugs. Amipride 50 can enhance the effects of CNS depressants (like narcotics and sedatives) and some blood pressure medications. Amipride 50 can be taken with or without food, as Amipride 50 does not affect absorption.
Contraindications
Amipride 50 is not recommended for people who are allergic to Amipride 50 or other components of the drug, or those with certain types of tumors like prolactinomas or breast cancer. Amipride 50 should also be avoided in children, pregnant or breastfeeding women, and people with certain heart conditions. People with liver problems may also need to avoid Amipride 50.
Side Effects
Common side effects include shaking, muscle stiffness, slow movement, drowsiness, dry mouth, constipation, dizziness, and weight gain. Less common effects are difficulty controlling facial or tongue movements, weak bones, and lung infections from choking. Amipride 50 may also cause increased levels of prolactin, leading to issues like breast pain or dysfunction in sexual health.
Pregnancy & Lactation
Amipride 50 is not recommended during pregnancy unless the benefits outweigh the risks. Amipride 50 can be found in breast milk, so breastfeeding is not advised while using this medication.
Precautions & Warnings
Patients taking Amipride 50 should be monitored for a serious condition called Neuroleptic Malignant Syndrome (NMS), which includes symptoms like high fever, muscle rigidity, and unstable blood pressure. Those with a history of seizures should be watched closely, and Amipride 50 should be stopped gradually to avoid withdrawal effects. Amipride 50 can also raise prolactin levels, leading to issues like lactation or menstrual problems.
Overdose Effects
Overdose symptoms can include drowsiness, low blood pressure, and severe movement disorders. In extreme cases, Amipride 50 can lead to coma. Fatal outcomes have been reported when combined with other drugs.
Therapeutic Class
Amipride 50 is classified as an atypical neuroleptic drug.
Storage Conditions
Store Amipride 50 below 30°C in a dry, cool place, away from light. Keep Amipride 50 out of the reach of children.
Similar Brands of Amisulpride (Tablet – 50mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Aride 50 | Tablet | 50mg | Renata Limited | 20.0 |