Anril Spray
Form: Spray
Strength: 400mcg
Generic Name: Glyceryl Trinitrate (nitroglycerine)
Company: Square Pharmaceuticals Ltd.
MRP:৳ 270.0 (200 metered doses)
Is Antibiotic: No
Indications
Anril Spray is used to treat high blood pressure during surgery, manage heart failure during a heart attack, treat chest pain in people who didn’t respond to other treatments, and help control blood pressure during surgery.
Pharmacology
Anril Spray works by relaxing blood vessels and widening both veins and arteries. This reduces the pressure in the heart and decreases blood flow resistance. Anril Spray also dilates coronary arteries, helping blood flow to the heart.
Dosage & Administration
Anril Spray is not given as a direct injection. The drug must be diluted in either a dextrose (5%) or sodium chloride (0.9%) solution before being infused. The initial dilution is made by transferring the contents of one ampoule into a 500 ml bottle of one of these solutions. The concentration should not exceed 400 mcg/ml.
Interaction
Its effects may be stronger when used with other blood pressure-lowering drugs. Anril Spray should not be mixed with blood or other medications. Anril Spray can also interfere with the effects of heparin, an anticoagulant, so careful monitoring is needed.
Contraindications
Anril Spray should not be used in people allergic to Anril Spray or in patients with certain heart conditions, such as pericardial tamponade, restrictive cardiomyopathy, or constrictive pericarditis.
Side Effects
The most common side effect is headache, which can be severe, especially with higher doses. Other possible side effects include lightheadedness, low blood pressure, and in rare cases, methemoglobinemia (a blood condition). Anril Spray may also cause fainting and chest pain.
Pregnancy & Lactation
Anril Spray is in pregnancy category C. Anril Spray is not known if Anril Spray passes into breast milk, so Anril Spray should only be used by nursing mothers if absolutely necessary.
Precautions & Warnings
Anril Spray should be used carefully in patients with low blood volume or low blood pressure. If blood pressure drops too much, Anril Spray can lead to slow heart rate, chest pain, and other complications. Long-term use can cause tolerance, reducing its effect, and sudden withdrawal can cause severe chest pain or even death.
Overdose Effects
An overdose can lead to serious effects like headache, confusion, dizziness, nausea, fainting, heart problems, difficulty breathing, and in extreme cases, seizures or death.
Therapeutic Class
Anril Spray belongs to the group of drugs called nitrates, used to widen coronary arteries.
Storage Conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.
Similar Brands of Glyceryl Trinitrate (nitroglycerine) (Spray – 400mcg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| GTN | Spray | 400mcg | Eskayef Pharmaceuticals Ltd. | 270.0 |
| Nidocard | Spray | 400mcg | Drug International Ltd. | 260.0 |
| Nitrin Sublingual | Spray | 400mcg | Healthcare Pharmaceuticals Ltd. | 270.0 |
| Nitrocard | Spray | 400mcg | Aristopharma Limited | 250.0 |
| Nitrosol | Spray | 400mcg | Beximco Pharmaceuticals Ltd. | 225.0 |
| Nitro Spray | Spray | 400mcg | Unimed Unihealth Pharmaceuticals Ltd. | 270.0 |
| Pactorin | Spray | 400mcg | ACI Limited | 250.0 |
| Trocer Spray | Spray | 400mcg | Incepta Pharmaceuticals Ltd. | 270.0 |