Tablet and Suspension:
Trichomoniasis (Adults & Children over 10 yrs):
200 mg three times a day or 400 mg twice a day for 7 days.
800 mg in the morning and 1-2 gm at night for 2 days.
2 gm once a day for 1 day.
Trichomoniasis (Children):
Children 7-10 yrs: 100 mg three times a day.
Children 3-7 yrs: 100 mg twice a day.
Children 1-3 yrs: 50 mg three times a day.
Intestinal Amoebiasis (Adults & Children over 10 yrs):
800 mg three times a day for 5 days.
Intestinal Amoebiasis (Children):
Children 7-10 yrs: 400 mg three times a day.
Children 3-7 yrs: 200 mg four times a day.
Children 1-3 yrs: 200 mg three times a day.
Extra-intestinal & Asymptomatic Amoebiasis (Adults & Children over 10 yrs):
400-800 mg three times a day for 5-10 days.
Extra-intestinal & Asymptomatic Amoebiasis (Children):
Children 7-10 yrs: 200-400 mg three times a day.
Children 3-7 yrs: 100-200 mg four times a day.
Children 1-3 yrs: 100-200 mg three times a day.
Giardiasis (Adults & Children over 10 yrs):
2 gm once a day for 3 days.
Giardiasis (Children):
Children 7-10 yrs: 1 gm once a day.
Children 3-7 yrs: 600-800 mg once a day.
Children 1-3 yrs: 500 mg once a day.
Acute Ulcerative Gingivitis (Adults & Children over 10 yrs):
200 mg three times a day for 3 days.
Acute Ulcerative Gingivitis (Children):
Children 7-10 yrs: 100 mg three times a day.
Children 3-7 yrs: 100 mg twice a day.
Children 1-3 yrs: 50 mg three times a day.
Acute Dental Infections (Adults & Children over 10 yrs):
200 mg three times a day for 3-7 days.
Bacterial Vaginosis (Adults & Children over 10 yrs):
400 mg twice a day for 7 days.
2 gm once a day for 1 day.
Leg Ulcers and Pressure Sores (Adults & Children over 10 yrs):
400 mg three times a day for 7 days.
Anaerobic Infections (Adults & Children over 10 yrs):
800 mg initially, then 400 mg three times a day for 7 days.
Anaerobic Infections (Children):
Children 1-10 yrs: 7.5 mg/kg three times a day.
Surgical Prophylaxis (Adults & Children over 10 yrs):
400 mg three times a day starting 24 hours before surgery for 1 day.
Surgical Prophylaxis (Children):
Children 1-10 yrs: 7.5 mg/kg three times a day.

Vaginal Gel:
One full applicator of gel (about 5 grams with 37.5 mg of the drug) is used once or twice a day for 5 days. Antipro is best to use Antipro at bedtime for once-a-day dosing.

Suppository:
Anaerobic Infections:
Adults: 1 gm every 8 hours for 3 days, then 1 gm every 12 hours.
Children: 5-10 years: 500 mg every 8 hours for 3 days, then every 12 hours, Over 10 years: adult dose.
Surgical Prophylaxis:
Adults: 1 gm 2 hours before surgery; up to 3 more doses of 1 gm every 8 hours for high-risk surgeries.
Children: 5-10 years: 500 mg 2 hours before surgery; up to 3 more doses of 500 mg every 8 hours for high-risk surgeries.

IV Infusion:
No dilution is required for IV infusion, and Antipro should not be mixed with other drugs before giving. The dose for adults and children over 12 years is 500 mg every 8 hours at a rate of 5 ml/min, with a maximum of 4 gm per day. Most patients need 7 days of treatment, but Antipro can be extended. For surgical prophylaxis, Antipro is given before surgery and then continued every 8 hours for the next 24 hours.
For children under 12 years, the dose is 7.5 mg/kg body weight per day, divided into 3 doses every 8 hours at a rate of 5 ml/min.