Clonipres ER 0.1
Form: Tablet
Strength: 100mcg
Generic Name: Clonidine Hydrochloride
Company: Navana Pharmaceuticals Ltd.
MRP:৳ 11.0 (Strip=10)
Per Piece: ৳ 1.10
Is Antibiotic: No
Indications
Clonipres ER 0.1 is used to treat high blood pressure. Clonipres ER 0.1 can be used alone or with other medicines to lower blood pressure. Clonipres ER 0.1 is also used to treat hot flashes during menopause, as well as to help with withdrawal symptoms from opioids and alcohol. The extended-release version is used to treat Attention Deficit Hyperactivity Disorder (ADHD) on its own.
Pharmacology
Clonipres ER 0.1 works by stimulating certain receptors in the brain. When taken in the immediate-release form, blood pressure starts to decrease within 30 to 60 minutes, with the most noticeable effect happening within 2 to 4 hours. The function of the kidneys stays the same, and normal body reflexes remain intact, so dizziness from standing up is rare.
Dosage & Administration
Adults: The dose should be adjusted based on how the patient responds to the treatment.
Initial dose: 0.1 mg twice a day (morning and evening). Elderly patients may need a lower starting dose.
Maintenance dose: The dose can be increased by 0.1 mg per day every week, if needed, until the desired effect is achieved. Common doses range from 0.2 mg to 0.6 mg per day in divided doses. If kidney problems are present, the dose must be adjusted and monitored carefully.
For ADHD: Immediate-release: 5 mcg/kg/day, Extended-release: 0.1 mg/day for 8 weeks.
For Menopausal Flushing: 0.1 mg to 0.4 mg per day.
For Alcohol Withdrawal: 0.3 to 0.6 mg every 6 hours or as prescribed by the doctor.
Use in Children & Adolescents: Safety and effectiveness have not been proven in children.
Interaction
Clonipres ER 0.1 can increase the effect of alcohol, barbiturates, and other sedatives. Clonipres ER 0.1 may also reduce the effectiveness of certain antidepressants (tricyclic). Be cautious when using Clonipres ER 0.1 with medicines like digitalis, calcium blockers, and beta-blockers, as Clonipres ER 0.1 can cause slow heart rate or other heart problems.
Contraindications
Clonipres ER 0.1 should not be used by people who are allergic to Clonipres ER 0.1.
Side Effects
The side effects are usually mild and get better with time. The most common side effects include dry mouth, feeling sleepy, dizziness, constipation, and feeling tired. Other side effects can include ear pain, irritability, stomach pain, nausea, and diarrhea.
Pregnancy & Lactation
Clonipres ER 0.1 should be avoided during pregnancy. Clonipres ER 0.1 can pass into breast milk, so use caution if you’re nursing.
Precautions & Warnings
Patients should not stop taking Clonipres ER 0.1 suddenly without talking to their doctor. Stopping suddenly can cause nervousness, headaches, shaking, and a sudden rise in blood pressure. If you need to stop taking the extended-release form, the dose should be reduced gradually over 2 to 4 days to avoid withdrawal symptoms. If you are taking a beta-blocker with Clonipres ER 0.1, the beta-blocker should be stopped before gradually stopping the Clonidine.
Overdose Effects
Taking too much can cause low blood pressure, slow heart rate, difficulty breathing, low body temperature, drowsiness, abnormal reflexes, weakness, and small pupils.
Therapeutic Class
Clonipres ER 0.1 belongs to the class of centrally acting antihypertensive drugs (central sympatholytic).
Storage Conditions
Store Clonipres ER 0.1 below 30°C, away from light and moisture. Keep Clonipres ER 0.1 out of reach of children.
Similar Brands of Clonidine Hydrochloride (Tablet – 100mcg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Clonipres 0.1 | Tablet | 100mcg | Navana Pharmaceuticals Ltd. | 10.0 |