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Clopidol

Form: Tablet

Strength: 75mg

Generic Name: Clopidogrel

Company: Alco Pharma Limited

MRP:৳ 10.0   (Tablet)

Is Antibiotic: No

Indications

Clopidol is used to reduce the chances of heart attack and stroke in patients with certain heart problems, like unstable angina or non-ST-elevation myocardial infarction (NSTEMI). Clopidol also helps reduce the rate of heart attack and stroke in patients with acute ST-elevation myocardial infarction (STEMI).

For people with recent heart attacks, strokes, or peripheral artery disease, Clopidol helps reduce the chances of more heart attacks and strokes.

Pharmacology

Clopidol is a prodrug that works by stopping platelets (blood cells) from sticking together. Clopidol does this by binding to specific receptors in platelets. You will see the effects of this within 2 hours of taking Clopidol, and after taking Clopidol for several days, Clopidol works even better.

Dosage & Administration

For Acute Coronary Syndrome: Start with a loading dose of 300 mg (4 tablets), followed by 75 mg daily. If you don’t start with the loading dose, Clopidol will take longer for the medicine to start working.

For Recent Heart Attacks, Strokes, or Peripheral Artery Disease: Take 75 mg once a day without a loading dose.

Clopidol can be taken with or without food.

Interaction

Taking Clopidol with NSAIDs, warfarin, or certain antidepressants (SSRIs, SNRIs) can increase the risk of bleeding. Avoid taking Clopidol with omeprazole or esomeprazole (medicines that block certain stomach acids). Clopidol should also not be taken with repaglinide, as Clopidol may cause higher levels of repaglinide in the blood.

Contraindications

Clopidol is not recommended for people who are allergic to Clopidol or any of its ingredients. Clopidol should also not be taken by people with active bleeding conditions like peptic ulcers or bleeding in the brain.

Side Effects

Clopidol is generally well tolerated. Some common side effects may include bleeding, diarrhea, stomach discomfort, and skin reactions. Rare side effects may include bleeding disorders, anemia, swelling, joint pain, or problems with the bone marrow.

Pregnancy & Lactation

There are no well-studied effects in pregnant women. Clopidol should only be used during pregnancy if absolutely necessary. Clopidol is also unknown if Clopidol passes into breast milk, so you should discuss whether to stop breastfeeding or stop the medicine with your doctor.

Precautions & Warnings

People who have a problem metabolizing Clopidol due to a genetic issue or because they are taking certain medications (like omeprazole or esomeprazole) may not get the full benefit of this medicine. Clopidol can increase the risk of bleeding, so be careful if you need surgery. If you stop taking Clopidol, you could have more heart problems. Clopidol should be stopped 5 days before surgery that could cause bleeding.

In rare cases, Clopidol can cause a serious condition called Thrombotic Thrombocytopenic Purpura (TTP), which requires immediate medical treatment.

Overdose Effects

Taking too much of this medicine may cause bleeding problems. In such cases, a platelet transfusion might be needed to help with clotting.

Therapeutic Class

Clopidol is an anti-platelet drug.

Storage Conditions

Keep Clopidol below 30°C, in a dry place, away from light. Do not freeze. Keep out of reach of children.

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