Clovir 400
Form: Tablet
Strength: 400mg
Generic Name: Acyclovir
Company: The Ibn Sina Pharmaceutical Ind. Ltd.
MRP:৳ 22.0 (Strip=10)
Per Piece: ৳ 2.20
Is Antibiotic: No
Indications
Clovir 400 is used to treat severe Herpes simplex in people with weak immune systems, serious genital herpes, chickenpox in weak immune patients, and shingles in those with severe symptoms. Clovir 400 also treats Herpes simplex infection in the brain.
Pharmacology
Clovir 400 works by stopping the virus from multiplying. Inside infected cells, Clovir 400 changes into its active form, which blocks the virus from making more DNA, preventing its spread.
Dosage & Administration
For Herpes simplex: 5 mg/kg every 8 hours.
For severe shingles: 5 mg/kg every 8 hours.
For chickenpox in weak immune patients: 10 mg/kg every 8 hours.
For brain infection from Herpes simplex: 10 mg/kg every 8 hours.
Each dose should be given as a slow IV infusion over one hour.
Interaction
Taking Clovir 400 with probenecid slows its removal from the body, increasing its effects. In older adults, using Clovir 400 with diuretics can raise its levels significantly.
Contraindications
Clovir 400 should not be used by people allergic to Clovir 400 or to Valacyclovir.
Side Effects
Some side effects include drowsiness, confusion, tremors, hallucinations, nausea, vomiting, skin rash, and increased liver enzymes. If injected incorrectly, Clovir 400 can cause swelling and irritation at the site.
Pregnancy & Lactation
Clovir 400 should only be used in pregnancy if the benefits outweigh the risks. If breastfeeding, Clovir 400 should only be taken if necessary.
Precautions & Warnings
Clovir 400 must be given slowly through IV and never by mouth. Patients should drink plenty of water to prevent kidney problems. Those with kidney disease, dehydration, or using other kidney-harming drugs should be cautious.
Overdose Effects
Overdose can cause kidney failure, confusion, hallucinations, agitation, seizures, and coma. Drinking water helps prevent crystal buildup in urine. Dialysis may be needed to remove excess drug.
Therapeutic Class
Treatment for Herpes simplex and Varicella-zoster infections.
Storage Conditions
Store between 15°C and 25°C, away from light and moisture. Keep out of children’s reach.
Similar Brands of Acyclovir (Tablet – 400mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Acerux 400 | Tablet | 400mg | Opsonin Pharma Limited | 22.0 |
| Acivir 400 | Tablet | 400mg | The ACME Laboratories Ltd. | 0.0 |
| D-Aciclovir | Tablet | 400mg | Delta Pharma Limited | 0.0 |
| Novirax 400 | Tablet | 400mg | Drug International Ltd. | 22.1 |
| Virunil | Tablet | 400mg | Globe Pharmaceuticals Ltd. | 22.0 |
| Virux 400 | Tablet | 400mg | Square Pharmaceuticals Ltd. | 22.14 |
| Xovir 400 | Tablet | 400mg | Beacon Pharmaceuticals Ltd. | 22.0 |