CoDiaglit 500
Form: Tablet
Strength: 500mg+15mg
Generic Name: Metformin Hydrochloride + Pioglitazone
Company: Beximco Pharmaceuticals Ltd.
MRP:৳ 10.0 (Tablet)
Is Antibiotic: No
Indications
CoDiaglit 500 is used along with diet and exercise to help control blood sugar in people with type 2 diabetes. This is for those who are already taking CoDiaglit 500 or those whose diabetes is not controlled well with just one of these medicines.
Pharmacology
CoDiaglit 500 works when insulin is present in the body. CoDiaglit 500 helps reduce insulin resistance in the body and liver, which leads to better use of insulin for glucose and reduces glucose made by the liver. CoDiaglit 500 is a strong medicine that helps control blood sugar by affecting genes involved in glucose and fat metabolism.
CoDiaglit 500 helps improve glucose tolerance by lowering blood sugar levels, both before and after meals. CoDiaglit 500 reduces glucose made by the liver, lowers glucose absorption from the intestines, and makes the body better at using insulin. Unlike other medicines, CoDiaglit 500 doesn’t cause low blood sugar or increase insulin levels in the body.
Dosage & Administration
General: The treatment for type 2 diabetes should be personalized based on how well CoDiaglit 500 works for the person. The daily dose should not exceed 45 mg of CoDiaglit 500 and 2550 mg of CoDiaglit 500.
Dosage Recommendations: The starting dose should be based on the person’s current medicine. CoDiaglit 500 should be taken in divided doses with meals to reduce side effects. The doses can be adjusted depending on how well CoDiaglit 500 works.
For patients switching from other treatments: CoDiaglit 500 may be started based on the dose of the previous medicine and adjusted as needed.
Maximum Dose: The maximum dose of CoDiaglit 500 is 45 mg a day, and the maximum dose of CoDiaglit 500 is 2550 mg a day for adults.
Special Patients: Older people and those with kidney problems may need lower doses. Kidney function should be checked regularly, especially for older people. This treatment should not be started if the liver is not working well.
Interaction
CoDiaglit 500 may affect vitamin B12 absorption. CoDiaglit 500 can also interact with other medicines, increasing or decreasing its effect. CoDiaglit 500 may interact with medicines that are cleared by the kidneys.
Contraindications
CoDiaglit 500 should not be used by people with kidney disease or dysfunction, especially if there is a high creatinine level or kidney problems from conditions like shock, heart attack, or infection. CoDiaglit 500 should also be avoided by those allergic to CoDiaglit 500 or any of its ingredients, and by those with metabolic acidosis, including diabetic ketoacidosis.
Side Effects
CoDiaglit 500 is generally well tolerated. The most common side effects are mild and include infections of the upper respiratory system, diarrhea, swelling of the legs, and headaches.
Pregnancy & Lactation
Pregnancy: There are no well-controlled studies for this medicine in pregnant women. CoDiaglit 500 should only be used if the potential benefits outweigh the risks to the baby.
Nursing mothers: CoDiaglit 500 is not known if CoDiaglit 500 is passed through breast milk. Because many medicines do pass through, CoDiaglit 500 should not be used while breastfeeding.
Precautions & Warnings
CoDiaglit 500 should not be used in people with type 1 diabetes or diabetic ketoacidosis. CoDiaglit 500 should be used carefully in people with liver or heart problems, or if CoDiaglit 500 is taken with insulin.
CoDiaglit 500 is cleared from the body through the kidneys, so people with kidney problems should not take CoDiaglit 500, especially if their creatinine levels are high.
Overdose Effects
If overdose occurs, appropriate treatment should be given based on the patient’s symptoms.
Therapeutic Class
Oral medicines for controlling blood sugar in people with diabetes.
Storage Conditions
Store in a cool, dry place. Keep CoDiaglit 500 away from light and moisture. Keep out of reach of children.
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