
Cofexin
Form: Syrup
Strength: 15mg/5ml
Generic Name: Ambroxol
Company: Globex Pharmaceuticals Ltd.
MRP:৳ 35.0 (100ml bot)
Is Antibiotic: No
Indications
Cofexin is used for productive cough and in conditions where the respiratory tract has thick mucus, such as acute and chronic bronchitis, asthma, and bronchiectasis. Cofexin is also helpful in treating inflammation of the nose and throat, such as sinusitis, pharyngitis, and rhinitis, that is linked with thick mucus. Cofexin can be used in chronic pneumonia and other related conditions.
Pharmacology
Cofexin is a product of bromhexine and works better than bromhexine itself to help clear mucus from the lungs. Cofexin thins the mucus in the airways, making Cofexin easier to cough up, which helps to breathe better. Cofexin also helps produce substances in the lungs that help keep them open. Additionally, Cofexin has anti-inflammatory effects that reduce inflammation in the airways, and Cofexin helps improve airflow in people with chronic lung conditions like COPD.
Dosage & Administration
Pediatric Drops:
0-6 months: 0.5 ml twice a day
6-12 months: 1 ml twice a day
1-2 years: 1.25 ml twice a day
Syrup:
2-5 years: 2.5 ml (1/2 teaspoon) 2-3 times a day
5-10 years: 5 ml (1 teaspoon) 2-3 times a day
10 years and adults: 10 ml (2 teaspoons) 3 times a day
Sustained release capsule:
Adults and children over 12 years: 1 capsule once daily
Interaction
Cofexin should not be taken with antitussive medicines like Codeine, as Cofexin may prevent the mucus that has been thinned from being coughed up.
Contraindications
Cofexin is not suitable for people who are allergic to Ambroxol or Bromhexine.
Side Effects
Some people may experience stomach discomfort, such as pain or a feeling of fullness. Rarely, allergic reactions like rashes or swelling may occur.
Pregnancy & Lactation
Studies on pregnant animals have shown no harmful effects, but Cofexin is advised not to use Cofexin during pregnancy, especially in the first trimester. Its safety during breastfeeding is not yet confirmed.
Precautions & Warnings
Cofexin should be used carefully in patients with stomach ulcers or those who have convulsions. People with liver or kidney problems should take Cofexin with caution.
Overdose Effects
N/A
Therapeutic Class
Cough expectorants & mucolytics
Storage Conditions
Store in a dry place, away from direct light, and keep the temperature below 30°C. Keep out of reach of children.
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