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Comfil

Form: Syrup

Strength: 1mg/5ml

Generic Name: Levosalbutamol

Company: Pharmasia Ltd.

MRP:৳ 38.0   (100ml bot)

Is Antibiotic: No

Indications

Comfil is used to treat or prevent bronchospasm (narrowing of the airways) in adults, teenagers, and children aged 6 years and older who have reversible obstructive airway disease.

Pharmacology

Comfil is a beta 2-agonist that works as a bronchodilator. Unlike racemic salbutamol, Comfil only contains the active isomer, which leads to effective bronchodilation with fewer side effects. This makes Comfil a good option for treating asthma with fewer beta-related side effects.

Dosage & Administration

Tablet:

Adults and adolescents above 12 years: 1-2 mg three times daily.
Children (6 – 11 years): 1 mg three times daily.

Syrup:
Adults: 5-10 ml three times daily.
Children (6 – 11 years): 5 ml three times daily.

Interaction

Other short-acting bronchodilators or epinephrine should be used cautiously with Comfil. If additional adrenergic drugs are needed, they should be used carefully to avoid heart problems.

Contraindications

Comfil is not recommended for people who are allergic to levosalbutamol or any of its ingredients.

Side Effects

Possible side effects include low calcium levels, palpitations, muscle tremors, and muscle cramps. Other side effects can be nausea, vomiting, chest pain, and diarrhea.

Pregnancy & Lactation

This medicine should only be used during pregnancy if the benefit outweighs the potential risk to the baby. Comfil is unknown whether Comfil is passed through breast milk, so caution is advised when breastfeeding.

Precautions & Warnings

Caution is advised in patients with severe asthma, especially if treated with other medications like steroids. Monitoring of potassium levels is recommended in these cases.

Overdose Effects

Symptoms of overdose include excessive stimulation of the heart and the side effects mentioned earlier. In cases of serious overdose, the stomach may need to be emptied, and a beta-blocker may be given with care in patients with a history of bronchospasm.

Therapeutic Class

Short-acting selective β2-adrenoceptor stimulants.

Storage Conditions

Keep out of reach of children. Store in a cool, dry place, away from light.

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