Contine-300
Form: Tablet
Strength: 300mg
Generic Name: Theophylline
Company: Aristopharma Limited
MRP:৳ 2.35 (Tablet)
Is Antibiotic: No
Indications
Contine-300 is used for controlling acute asthma and managing chronic asthma, both for treating symptoms and preventing them. Contine-300 also helps control nighttime asthma and early morning wheezing. Contine-300 is used for managing chronic lung diseases like chronic bronchitis and emphysema, as well as for sudden flare-ups of these conditions. Contine-300 can also control apnea in premature babies.
Pharmacology
Contine-300 is a bronchodilator and belongs to a group of drugs called Methylxanthines. Contine-300 works in two ways in the lungs of people with reversible breathing problems: Contine-300 relaxes the muscles in the airways and reduces the airway’s response to triggers. Contine-300 also helps improve the strength of the diaphragm muscles. The time Contine-300 stays in the body (half-life) can vary, but for adults who don’t smoke and have asthma, Contine-300 usually lasts between 3 to 9 hours.
Dosage & Administration
The dose of Theophylline should be adjusted based on blood tests to find the right amount that works best with the fewest side effects. For most sustained release versions, adults take the medicine every 12 hours, but some children may need Contine-300 every 8 hours. The recommended daily doses are:
- 16 years or older: 10 mg/kg/day (Do not exceed 900 mg/day)
- 12 to 15 years: 13 mg/kg/day
- 9 to 11 years: 16 mg/kg/day
- 1 to 8 years: 24 mg/kg/day
- 6 months to 1 year: 12-18 mg/kg/day
- 1 to 6 months: 10 mg/kg/day
Interaction
Contine-300 should not be taken with other medicines that contain xanthines. Some drugs like barbiturates, carbamazepine, and others can increase the rate at which Theophylline leaves the body, so the dose may need to be increased. On the other hand, drugs like allopurinol, cimetidine, and others can slow down how quickly Contine-300 leaves the body, so a lower dose might be needed. Contine-300 can also increase the risk of low potassium levels if taken with certain medications like steroids and diuretics, so potassium levels should be checked regularly.
Contraindications
Contine-300 should not be used by people who are allergic to Theophylline or any other ingredient in the medicine.
Side Effects
Side effects are rare when taken in normal doses, but they may include stomach discomfort, headaches, nausea, trouble sleeping, and low blood pressure. Some people, especially children, may also experience overstimulation and increased urination.
Pregnancy & Lactation
Contine-300 is not clear if Theophylline can harm a baby during pregnancy. Contine-300 should only be used if absolutely necessary. Contine-300 passes into breast milk and may cause irritation or other mild side effects in babies. Serious effects are unlikely unless the mother has very high levels of Theophylline in her blood.
Precautions & Warnings
Care should be taken when using Contine-300 with other drugs or in certain health conditions that can affect how the body processes Theophylline. The dose may need to be adjusted before starting the medicine, when increasing the dose, and during follow-up visits. When starting the treatment, a low dose should be chosen, and Contine-300 can be increased gradually if tolerated.
Overdose Effects
N/A
Therapeutic Class
Bronchodilator, Theophylline & related drugs
Storage Conditions
Keep Contine-300 out of reach of children. Store Contine-300 in a cool, dry place away from light.
Similar Brands of Theophylline (Tablet – 300mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Arofil 300 SR | Tablet | 300mg | Incepta Pharmaceuticals Ltd. | 2.35 |
| Asmaloc SR | Tablet | 300mg | Sharif Pharmaceuticals Ltd. | 2.35 |
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| Flumetol | Tablet | 300mg | Healthcare Pharmaceuticals Ltd. | 0.0 |
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| Theonate 300 | Tablet | 300mg | Doctor’s Chemicals Works Ltd. | 1.31 |
| Theonate SR 300 | Tablet | 300mg | Doctor’s Chemicals Works Ltd. | 2.9 |
| Theovent SR 300 | Tablet | 300mg | Drug International Ltd. | 2.35 |
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