Cortisol
Form: Oral Solution
Strength: 5mg/5ml
Generic Name: Prednisolone
Company: Aristopharma Limited
MRP:৳ 65.0 (50ml bot)
Is Antibiotic: No
Indications
Cortisol is used to treat various conditions like rheumatoid arthritis, severe allergic reactions, asthma, and skin diseases. Cortisol is also prescribed for disorders related to the blood, eyes, and glands like the adrenal glands.
Pharmacology
Cortisol is a synthetic steroid that mainly reduces inflammation. Cortisol works by stopping certain enzymes in the body from causing inflammation. Prednisolone is absorbed quickly by the body and binds to proteins in the blood. Cortisol is processed in the liver and removed from the body through urine.
Dosage & Administration
Adult: For conditions like nephrotic syndrome, the starting dose is 2 mg/kg/day (max 80 mg/day) divided into 3–4 doses. After 28 days, reduce the dose. For inflammation, the dose varies from 5 to 60 mg per day.
Pediatric: For asthma, children aged 1–12 years are given 10–40 mg every 12 hours, depending on age. For other conditions, doses are usually between 0.05 to 2 mg/kg per day.
Interaction
Cortisol may interact with drugs like barbiturates, rifampin, and antacids. Cortisol can also lower potassium levels, which may cause heart issues if combined with other heart medications.
Contraindications
Cortisol should not be used in patients with active infections or known hypersensitivity to its ingredients. Cortisol is also contraindicated in cases of eye herpes infection due to risk of complications.
Side Effects
Common side effects include increased appetite, indigestion, and nervousness. Less common side effects may include dizziness, skin color changes, sweating, and feeling lightheaded.
Pregnancy & Lactation
Cortisol is not recommended during pregnancy unless necessary. Cortisol can pass into breast milk and may affect the baby, so caution is advised when using Cortisol while breastfeeding.
Precautions & Warnings
Cortisol should be used with care in people with conditions like diabetes, high blood pressure, and osteoporosis. Long-term use can lead to weight gain, increased blood sugar, muscle weakness, and other health issues.
Overdose Effects
Overdose effects typically occur with long-term high doses. Treatment is mainly supportive, and doses should be reduced gradually under medical supervision.
Therapeutic Class
Cortisol belongs to the class of glucocorticoid steroids.
Storage Conditions
Store in a cool, dry place away from light. Keep out of reach of children.
Similar Brands of Prednisolone (Oral Solution – 5mg/5ml)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Cortan 100ml | Oral Solution | 5mg/5ml | Incepta Pharmaceuticals Ltd. | 95.0 |
| Deltasone | Oral Solution | 5mg/5ml | Renata Limited | 60.0 |
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| Precodil 5 (100ml) | Oral Solution | 5mg/5ml | Opsonin Pharma Limited | 95.29 |
| Precodil 5 (50ml) | Oral Solution | 5mg/5ml | Opsonin Pharma Limited | 65.19 |
| Solone Oral Sol | Oral Solution | 5mg/5ml | ACI Limited | 65.0 |
| Solone Oral Sol | Oral Solution | 5mg/5ml | ACI Limited | 101.2 |