Cosat
Form: Suspension
Strength: 200mg+40mg/5ml
Generic Name: Sulphamethoxazole + Trimethoprim (Co-trimoxazole)
Company: Eskayef Pharmaceuticals Ltd.
MRP:৳ 22.0 (60ml bot)
Is Antibiotic: Yes
Indications
Cosat is used to treat various infections caused by bacteria, including respiratory tract infections like bronchitis, pneumonia, and sinusitis. Cosat is also used for genito-urinary infections, such as urinary tract infections and gonorrhoea, as well as gastrointestinal infections caused by certain bacteria. Cosat is also used for infections like osteomyelitis, skin infections, and some parasitic infections.
Pharmacology
Cosat is a combination of two drugs, Trimethoprim and Sulphamethoxazole, which work together to block bacterial enzymes, stopping the production of folic acid in the bacteria, leading to their death. This combination is effective against a wide range of bacteria and some protozoa.
Dosage & Administration
For individuals over 12 years:
For mild to moderate infections: 1 tablet twice a day.
For severe infections: 1.5 tablets twice a day.
For long-term therapy (more than 14 days): 0.5 tablet twice a day.
For gonorrhoea: 2 tablets every 12 hours for 2 days or 2.5 tablets followed by another dose after 8 hours.
For individuals under 12 years (Suspension form):
6-12 years: 2 teaspoonfuls twice a day.
6 months-5 years: 1 teaspoonful twice a day.
6 weeks-6 months: 0.5 teaspoonful twice a day.
Interaction
There are no known significant interactions.
Contraindications
Cosat is contraindicated in patients who are allergic to trimethoprim or sulphonamides, or those with folate deficiency, severe liver or kidney problems, or certain blood conditions.
Side Effects
Cosat may cause mild side effects like headache, nausea, vomiting, or feeling unwell. Rare side effects include skin reactions, blood disorders, and allergic reactions. Most of these side effects are mild and temporary.
Pregnancy & Lactation
Cosat should not be used during pregnancy or breastfeeding, as Cosat can pass to the baby and cause harm, such as jaundice or kernicterus.
Precautions & Warnings
Cosat should be used with caution in patients with diabetes or those taking certain diabetes medications. Long-term use can lead to a type of anemia, which can be treated with folinic acid. Cosat is also important to monitor for signs of low folate levels, especially during prolonged treatment.
Overdose Effects
No specific information is available for overdose effects.
Therapeutic Class
Cosat belongs to the class of anti-diarrhoeal antimicrobial drugs, sulphonamides, and trimethoprim.
Storage Conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.
Similar Brands of Sulphamethoxazole + Trimethoprim (Co-trimoxazole) (Suspension – 200mg+40mg/5ml)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Actrim | Suspension | 200mg+40mg/5ml | Globe Pharmaceuticals Ltd. | 22.0 |
| Albutrim | Suspension | 200mg+40mg/5ml | Albion Laboratories Ltd. | 20.0 |
| Alcot | Suspension | 200mg+40mg/5ml | Pacific Pharmaceuticals Ltd. | 20.0 |
| Apcetrim | Suspension | 200mg+40mg/5ml | APC Pharma Limited | 22.0 |
| Apcetrim | Suspension | 200mg+40mg/5ml | APC Pharma Limited | 22.0 |
| Aptrim | Suspension | 200mg+40mg/5ml | Apollo Pharmaceutical Laboratories Ltd. | 20.54 |
| Avlotrin | Suspension | 200mg+40mg/5ml | ACI Limited | 22.21 |
| Bactipront | Suspension | 200mg+40mg/5ml | Renata Limited | 22.06 |
| Biotrim | Suspension | 200mg+40mg/5ml | Biopharma Ltd. | 22.0 |
| Cotrazen | Suspension | 200mg+40mg/5ml | Zenith Pharmaceuticals Ltd. | 21.36 |
| Cotrimoxazole | Suspension | 200mg+40mg/5ml | Popular Pharmaceuticals Ltd. | 22.06 |
| Cotrimox | Suspension | 200mg+40mg/5ml | Indo-Bangla Pharmaceuticals Ltd. | 21.0 |
| Cotrim | Suspension | 200mg+40mg/5ml | Square Pharmaceuticals Ltd. | 21.64 |
| Cots | Suspension | 200mg+40mg/5ml | Opsonin Pharma Limited | 22.21 |
| Ditrim | Suspension | 200mg+40mg/5ml | Drug International Ltd. | 21.39 |
| Doctrim | Suspension | 200mg+40mg/5ml | Doctor’s Chemicals Works Ltd. | 22.0 |
| Editrim | Suspension | 200mg+40mg/5ml | Edruc Ltd. | 20.23 |
| Gentrim | Suspension | 200mg+40mg/5ml | General Pharmaceuticals Ltd. | 22.13 |
| G Cotrimoxazole | Suspension | 200mg+40mg/5ml | Gonoshasthaya Pharmaceuticals Ltd. | 30.0 |
| Jasotrim | Suspension | 200mg+40mg/5ml | Jayson Pharmaceuticals Ltd. | 21.68 |
| K Trim | Suspension | 200mg+40mg/5ml | Kemiko Pharmaceuticals Ltd. | 17.51 |
| Litrim | Suspension | 200mg+40mg/5ml | Millat Pharmaceuticals Ltd. | 21.5 |
| Meditrim | Suspension | 200mg+40mg/5ml | Medimet Pharmaceuticals Ltd. | 20.0 |
| Megatrim | Suspension | 200mg+40mg/5ml | Beximco Pharmaceuticals Ltd. | 22.17 |
| Navatrim | Suspension | 200mg+40mg/5ml | Navana Pharmaceuticals Ltd. | 21.07 |
| Neoset | Suspension | 200mg+40mg/5ml | Alco Pharma Limited | 20.99 |
| Octrim | Suspension | 200mg+40mg/5ml | Orion Pharma Ltd. | 21.08 |
| Politrim | Suspension | 200mg+40mg/5ml | The ACME Laboratories Ltd. | 21.65 |
| Saltrim | Suspension | 200mg+40mg/5ml | Salton Pharmaceuticals Ltd. | 21.08 |
| Seftrim | Suspension | 200mg+40mg/5ml | Hudson Pharmaceuticals Ltd. | 22.0 |
| Semotrim | Suspension | 200mg+40mg/5ml | Reliance Pharmaceuticals Ltd. | 22.0 |
| Semotrim | Suspension | 200mg+40mg/5ml | Reliance Pharmaceuticals Ltd. | 20.6 |
| Septra | Suspension | 200mg+40mg/5ml | Asiatic Laboratories Ltd. | 21.57 |
| Sinatrim | Suspension | 200mg+40mg/5ml | The Ibn Sina Pharmaceutical Ind. Ltd. | 22.0 |
| Sitrim | Suspension | 200mg+40mg/5ml | Silva Pharmaceuticals Ltd. | 20.07 |
| Sulprim | Suspension | 200mg+40mg/5ml | Somatec Pharmaceuticals Ltd. | 21.07 |
| Sumetrolim | Suspension | 200mg+40mg/5ml | Ambee Pharmaceuticals Ltd. | 21.61 |
| Suprim | Suspension | 200mg+40mg/5ml | Nipa Pharmaceuticals Ltd. | 0.0 |
| Sytrim | Suspension | 200mg+40mg/5ml | MST Pharma and Healthcare Ltd. | 21.25 |
| Tricot | Suspension | 200mg+40mg/5ml | Reman Drug Laboratories Ltd. | 21.5 |
| Trimetrin | Suspension | 200mg+40mg/5ml | Gaco Pharmaceuticals(G.A Company Ltd) | 21.0 |