Coveram 4/5
Form: tablet
Strength: 4mg+5mg
Generic Name: Perindopril + Amlodipine
Company: Servier Bangladesh
MRP:৳ 22.0 (Box=30)
Per Piece: ৳ 0.73
Is Antibiotic: No
Indications
Coveram 4/5 is used as a substitute treatment for high blood pressure and/or stable heart disease in patients who are already taking perindopril and amlodipine separately at the same dose. Coveram 4/5 should not be started as the first treatment.
Pharmacology
Coveram 4/5 is made of two medicines: Perindopril and Amlodipine. Perindopril helps lower blood pressure by blocking an enzyme (ACE), which reduces a hormone that can narrow blood vessels. This results in the vessels relaxing and blood pressure going down. Amlodipine works by blocking calcium from entering blood vessels, which relaxes and widens the vessels, helping blood flow more easily.
Dosage & Administration
Adults: Take one tablet per day, preferably in the morning before a meal. If needed, the dose can be adjusted by using the separate medicines of perindopril and amlodipine until the right dose is found.
Note: The treatment should not be started with this combination. Be cautious of food intake as Coveram 4/5 may affect how perindopril works.
Interaction
Coveram 4/5 is important to monitor blood pressure and kidney function, especially if combined with Baclofen or other blood pressure medications like nitroglycerine, as this may further lower blood pressure.
Contraindications
Coveram 4/5 is not suitable for patients who have had an allergic reaction to perindopril, amlodipine, or other similar medicines, or during pregnancy and breastfeeding.
Side Effects
The common side effects include swelling, drowsiness, dizziness, headaches, changes in taste, numbness, vision problems, ringing in ears, and a few digestive issues like nausea or diarrhea. Muscle pain and tiredness may also occur.
Pregnancy & Lactation
Coveram 4/5 should not be started during pregnancy or breastfeeding. If you are pregnant, stop using this combination and consult your doctor for other treatments.
Precautions & Warnings
Patients with rare conditions like galactose intolerance should avoid this medicine. Regular tests should be done to monitor potassium levels and kidney function while using this treatment.
Overdose Effects
N/A
Therapeutic Class
Coveram 4/5 is a combined treatment for high blood pressure.
Storage Conditions
Store in a dry place below 25°C. Keep the container tightly closed and protect from light.