Coversyl Plus
Form: tablet
Strength: 4mg+1.25mg
Generic Name: Indapamide + Perindopril Erbumine
Company: Servier Bangladesh
MRP:৳ 23.0 (Box=30)
Per Piece: ৳ 0.77
Is Antibiotic: No
Indications
Coversyl Plus is used to treat high blood pressure when blood pressure is not well controlled by perindopril alone.
Pharmacology
Perindopril is a medicine used to treat high blood pressure. After you take Coversyl Plus, the body turns Coversyl Plus into an active form called perindoprilat. Perindopril stops a substance called angiotensin II from being formed. This helps blood vessels relax and lowers blood pressure. Coversyl Plus may also increase the level of potassium in the blood. Perindopril affects the body’s balance of a substance called renin, which helps regulate blood pressure.
Indapamide is a type of diuretic (water pill). Coversyl Plus helps the body get rid of excess salt and water by making you urinate more. This helps lower blood pressure. Coversyl Plus also increases the amount of potassium and magnesium your body loses in urine.
Dosage & Administration
Adults: Take 1-2 tablets a day, preferably in the morning before a meal. If you have kidney problems, the doctor may start you on a lower dose.
Interaction
If you take this medicine with other blood pressure medications or antipsychotic drugs, Coversyl Plus may lower your blood pressure too much. Non-steroidal anti-inflammatory drugs (NSAIDs) may reduce its blood pressure-lowering effect. Taking Coversyl Plus with ARBs or potassium-sparing diuretics can increase potassium levels in the blood.
Contraindications
Coversyl Plus is not safe for people who are allergic to perindopril, indapamide, or any other ACE inhibitors.
Side Effects
Possible side effects include nausea, vomiting, upset stomach, diarrhea, constipation, headache, dizziness, trouble sleeping, weakness, dry mouth, low blood pressure, dry cough, swelling, and rash.
Pregnancy & Lactation
There are no well-controlled studies on pregnant women. Coversyl Plus is not recommended during pregnancy. If you are breastfeeding, do not take this medicine.
Precautions & Warnings
Use carefully in patients with kidney problems, heart failure, gout, diabetes, liver disease, elderly patients, and those with a history of swelling (angioedema).
Overdose Effects
Overdose symptoms may include low blood pressure, nausea, vomiting, cramps, dizziness, sleepiness, confusion, and decreased urine. Coversyl Plus can also cause problems with sodium and potassium levels. Treatment may include stomach pumping or using activated charcoal, and fluid and electrolyte balance should be maintained.
Therapeutic Class
Combined antihypertensive preparations.
Storage Conditions
Store below 30°C.