Curazith
Form: Tablet
Strength: 250mg
Generic Name: Azithromycin
Company: Sanofi Bangladesh Ltd.
MRP:৳ 20.06 (Box=6)
Per Piece: ৳ 3.34
Is Antibiotic: Yes
Indications
Curazith is used to treat bacterial eye infections caused by certain bacteria like CDC coryneform group G, Haemophilus influenzae, Staphylococcus aureus, Streptococcus mitis group, and Streptococcus pneumonia.
Pharmacology
Curazith is stable in acid and can be taken orally without needing protection from stomach acid. Curazith is absorbed easily, especially when taken on an empty stomach. After taking Curazith, the highest level in the body is reached in 2.1 to 3.2 hours. Curazith is concentrated in the white blood cells and is delivered to the infection site. The drug is stored in the tissues and released over time, with levels in tissues being over 50 times higher than in the blood. This allows a single dose to remain effective for several days. After one dose, Curazith stays in the body for up to 68 hours. Curazith is mainly eliminated through bile, with a small amount leaving the body unchanged in urine.
Microbiology
Curazith works by binding to a part of bacteria, stopping them from making proteins, which prevents the bacteria from growing. Curazith does not affect the bacteria’s genetic material. Curazith is effective against many bacteria, including:
- Gram-positive bacteria like Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes.
- Gram-negative bacteria like Haemophilus influenzae, Neisseria gonorrhoeae, and Moraxella catarrhalis.
- Other bacteria like Chlamydia pneumoniae, Mycoplasma pneumoniae, and Chlamydia trachomatis.
Curazith works even against some bacteria that produce betalactamase, an enzyme that makes other antibiotics less effective.
Dosage & Administration
Adults and children 1 year and older: Put 1 drop in the affected eye(s) twice a day for the first 2 days, then once a day for the next 5 days.
Pediatric use: Curazith has not been tested in children under 1 year of age, so Curazith is not recommended for them.
Interaction
No interaction studies have been done with Azithromycin Eye Drops.
Contraindications
Curazith should not be used by anyone who is allergic to any of its ingredients.
Side Effects
Possible side effects include eye irritation, skin irritation, corneal damage, dry eyes, and inflammation of the cornea.
Pregnancy & Lactation
Curazith is classified as Pregnancy Category B, meaning no harm was found in animal studies. However, Curazith should only be used during pregnancy if absolutely necessary. Curazith is not known if Curazith passes into breast milk, so caution is advised when using Curazith while nursing.
Precautions & Warnings
Curazith is only for use in the eyes. Curazith should not be used in the bloodstream, injected into the eye, or placed into the inner part of the eye.
Overdose Effects
No specific overdose effects have been reported.
Therapeutic Class
Curazith belongs to the Macrolide class of antibiotics.
Storage Conditions
Store the unopened bottle in the fridge between 2°C to 8°C. After opening, keep Curazith at room temperature (25°C) for up to 14 days. Discard Curazith after 14 days.
Similar Brands of Azithromycin (Tablet – 250mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Asizith | Tablet | 250mg | Asiatic Laboratories Ltd. | 20.0 |
| Azicin 250 | Tablet | 250mg | Opsonin Pharma Limited | 25.0 |
| Azilab 250 | Tablet | 250mg | Labaid Pharmaceuticals Ltd. | 0.0 |
| Azimex 250 | Tablet | 250mg | Drug International Ltd. | 25.1 |
| Azinil | Tablet | 250mg | Apex Pharma Ltd. | 25.0 |
| Azithrocin 250 | Tablet | 250mg | Beximco Pharmaceuticals Ltd. | 25.0 |
| AZ 250 | Tablet | 250mg | Aristopharma Limited | 30.0 |
| Maczith | Tablet | 250mg | Biopharma Ltd. | 25.0 |
| Myzid | Tablet | 250mg | Ambee Pharmaceuticals Ltd. | 0.0 |
| Rozith | Tablet | 250mg | Healthcare Pharmaceuticals Ltd. | 30.0 |
| Thromax | Tablet | 250mg | Novo Healthcare and Pharma Ltd. | 20.0 |
| Tridosil | Tablet | 250mg | Incepta Pharmaceuticals Ltd. | 25.0 |
| Zibac | Tablet | 250mg | Popular Pharmaceuticals Ltd. | 30.0 |
| Zinex | Tablet | 250mg | Alco Pharma Limited | 20.0 |
| Zithrin 250 Tablet | Tablet | 250mg | Renata Limited | 25.0 |
| Zithrox 250 | Tablet | 250mg | Eskayef Pharmaceuticals Ltd. | 25.0 |