Cytomis 200
Form: Tablet
Strength: 200mcg
Generic Name: Misoprostol
Company: Incepta Pharmaceuticals Ltd.
MRP:৳ 15.0 (Strip=10)
Per Piece: ৳ 1.50
Is Antibiotic: No
Indications
Cytomis 200 is used to prevent stomach and duodenal ulcers in people taking NSAIDs who are at high risk of complications. Cytomis 200 is also used to heal existing ulcers caused by NSAIDs, heal ulcers without NSAID use, induce labor, and prevent or treat postpartum bleeding.
Pharmacology
Cytomis 200 is absorbed in the body and quickly changes into its active form, which works in the body. The acid form of Misoprostol is less effective when taken with food or with certain antacids. Cytomis 200 helps reduce stomach acid and protects the stomach lining, especially when NSAIDs reduce protective prostaglandins. Cytomis 200 can increase protective substances like mucus and bicarbonate in the stomach, which may help prevent damage caused by NSAIDs, though Cytomis 200’s unclear if Cytomis 200 works through one effect or both.
Dosage & Administration
For gastric and duodenal ulcers: 800 mcg daily in 2-4 doses with meals and at bedtime. Treatment should last at least 4 weeks, up to 8 weeks if needed.
To prevent NSAID-induced ulcers: 200 mcg 2-4 times daily with NSAIDs. If this dose is not tolerated, 100 mcg can be used.
For labor induction: Place 25 mcg in the vagina, repeating every 6 hours until reaching 200 mcg total. Monitor heart rate and contractions. Alternatively, 100 mcg orally. If labor does not start, give 100-200 mcg every 4 hours until labor starts, up to 6 doses. Oxytocin can be used 4 hours after the last dose. Notify the physician if signs of fetal distress or abnormal contractions appear.
For postpartum bleeding prevention: 600 mcg orally right after delivery.
For treating postpartum bleeding: 600 mcg orally or 1000 mcg rectally.
Interaction
There are no significant interactions with cardiac, lung, CNS drugs, or NSAIDs. However, the bioavailability of Misoprostol may decrease when taken with high doses of antacids.
Contraindications
Cytomis 200 is contraindicated for those allergic to prostaglandins and during pregnancy.
Side Effects
Cytomis 200 is generally well tolerated. Some people may experience stomach issues like diarrhea, abdominal pain, nausea, vomiting, bloating, or dizziness. Taking Cytomis 200 after meals and at bedtime, as well as avoiding antacids with magnesium, can help reduce these side effects.
Pregnancy & Lactation
Cytomis 200 is not safe during pregnancy due to its potential to cause miscarriage. Cytomis 200 should not be used unless absolutely necessary, such as when NSAID therapy is required and there is a high risk of stomach or duodenal ulcers. Women of childbearing age must use reliable contraception during treatment. Cytomis 200 may pass into breast milk, but its effects on nursing infants are not well studied, so Cytomis 200 is not recommended for breastfeeding mothers.
Precautions & Warnings
Cytomis 200 should not be used by pregnant women and must only be prescribed to women of childbearing age if they need NSAID therapy. Women must confirm they are not pregnant and use effective contraception during treatment.
For labor induction, the pregnancy must be 38 weeks or more. Induction should not occur in cases of acute fetal distress, placenta previa, or unexplained bleeding. The fetus should also be in the correct position for delivery.
Overdose Effects
Overdose symptoms may include drowsiness, tremors, seizures, difficulty breathing, abdominal pain, diarrhea, and fever. Treatment should focus on supportive care.
Therapeutic Class
Cytomis 200 is classified as a prostaglandin analogue used to treat conditions affecting the uterus.
Storage Conditions
Store Cytomis 200 in a cool, dry place away from light and moisture. Keep Cytomis 200 out of the reach of children.
Similar Brands of Misoprostol (Tablet – 200mcg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Aboprost 200 | Tablet | 200mcg | Benham Pharmaceuticals Ltd. | 14.5 |
| G-Misoprostol | Tablet | 200mcg | Gonoshasthaya Pharmaceuticals Ltd. | 12.0 |
| G- Misoprostol | Tablet | 200mcg | Gonoshasthaya Pharmaceuticals Ltd. | 10.04 |
| Indula | Tablet | 200mcg | Renata Limited | 15.0 |
| Isovent 200 | Tablet | 200mcg | Square Pharmaceuticals Ltd. | 15.1 |
| Miptol | Tablet | 200mcg | The ACME Laboratories Ltd. | 15.0 |
| Misopa 200 | Tablet | 200mcg | Beximco Pharmaceuticals Ltd. | 15.0 |
| Misopil | Tablet | 200mcg | General Pharmaceuticals Ltd. | 15.0 |
| Misotab | Tablet | 200mcg | Euro Pharma Ltd. | 15.0 |
| Misotol | Tablet | 200mcg | Ziska Pharmaceuticals Ltd. | 15.0 |