D-Aciclovir
Form: Tablet
Strength: 400mg
Generic Name: Acyclovir
Company: Delta Pharma Limited
MRP:৳ 0.0 (Tablet)
Is Antibiotic: No
Indications
D-Aciclovir is used to treat severe Herpes simplex in people with weak immune systems, serious genital herpes, chickenpox in weak immune patients, and shingles in those with severe symptoms. D-Aciclovir also treats Herpes simplex infection in the brain.
Pharmacology
D-Aciclovir works by stopping the virus from multiplying. Inside infected cells, D-Aciclovir changes into its active form, which blocks the virus from making more DNA, preventing its spread.
Dosage & Administration
For Herpes simplex: 5 mg/kg every 8 hours.
For severe shingles: 5 mg/kg every 8 hours.
For chickenpox in weak immune patients: 10 mg/kg every 8 hours.
For brain infection from Herpes simplex: 10 mg/kg every 8 hours.
Each dose should be given as a slow IV infusion over one hour.
Interaction
Taking D-Aciclovir with probenecid slows its removal from the body, increasing its effects. In older adults, using D-Aciclovir with diuretics can raise its levels significantly.
Contraindications
D-Aciclovir should not be used by people allergic to D-Aciclovir or to Valacyclovir.
Side Effects
Some side effects include drowsiness, confusion, tremors, hallucinations, nausea, vomiting, skin rash, and increased liver enzymes. If injected incorrectly, D-Aciclovir can cause swelling and irritation at the site.
Pregnancy & Lactation
D-Aciclovir should only be used in pregnancy if the benefits outweigh the risks. If breastfeeding, D-Aciclovir should only be taken if necessary.
Precautions & Warnings
D-Aciclovir must be given slowly through IV and never by mouth. Patients should drink plenty of water to prevent kidney problems. Those with kidney disease, dehydration, or using other kidney-harming drugs should be cautious.
Overdose Effects
Overdose can cause kidney failure, confusion, hallucinations, agitation, seizures, and coma. Drinking water helps prevent crystal buildup in urine. Dialysis may be needed to remove excess drug.
Therapeutic Class
Treatment for Herpes simplex and Varicella-zoster infections.
Storage Conditions
Store between 15°C and 25°C, away from light and moisture. Keep out of children’s reach.
Similar Brands of Acyclovir (Tablet – 400mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Acerux 400 | Tablet | 400mg | Opsonin Pharma Limited | 22.0 |
| Acivir 400 | Tablet | 400mg | The ACME Laboratories Ltd. | 0.0 |
| Clovir 400 | Tablet | 400mg | The Ibn Sina Pharmaceutical Ind. Ltd. | 22.0 |
| Novirax 400 | Tablet | 400mg | Drug International Ltd. | 22.1 |
| Virunil | Tablet | 400mg | Globe Pharmaceuticals Ltd. | 22.0 |
| Virux 400 | Tablet | 400mg | Square Pharmaceuticals Ltd. | 22.14 |
| Xovir 400 | Tablet | 400mg | Beacon Pharmaceuticals Ltd. | 22.0 |