Daclaxen
Form: Tablet
Strength: 60mg
Generic Name: Daclatasvir
Company: Everest Pharmaceuticals Ltd.
MRP:৳ 400.0 (Box=28)
Per Piece: ৳ 14.29
Is Antibiotic: No
Indications
Daclaxen is used in combination with Sofosbuvir to treat chronic Hepatitis C virus (HCV) infection in adults.
Pharmacology
Daclaxen is a direct-acting antiviral agent (DAA) that targets the Hepatitis C Virus (HCV). Daclaxen works by blocking a protein (NS5A) that HCV needs to reproduce. By binding to this protein, Daclaxen stops the virus from making copies and assembling new virus particles.
Dosage & Administration
Recommended Dosage: Take 60 mg once a day, with or without food. Daclaxen must be used together with other medications for best results. For specific regimens and treatment durations, consult the product details.
If a dose is missed within 20 hours of the scheduled time, take Daclaxen as soon as possible. If Daclaxen’s more than 20 hours late, skip the dose and take the next one at the regular time.
Interaction
Daclaxen can be affected by medications that change its breakdown in the body. Drugs that strongly increase certain enzymes (CYP3A) can reduce its effectiveness, while those that decrease these enzymes can increase its concentration. Daclaxen may also impact other medications processed by certain transporters in the body.
Contraindications
Daclaxen should not be used with medicines that strongly increase the CYP3A enzyme, such as certain anticonvulsants, tuberculosis drugs, and St. John’s Wort.
Side Effects
Serious side effects may include slow heart rate (bradycardia) when taken with Amiodarone and Sofosbuvir. Symptoms of this include dizziness, fainting, weakness, shortness of breath, and chest pain.
Pregnancy & Lactation
There is no information available on the safety of this drug during pregnancy or breastfeeding. Consult your doctor before use.
Precautions & Warnings
Drug interactions can affect its effectiveness or cause serious side effects. If taken with Amiodarone, heart monitoring is advised due to the risk of slow heart rate.
Overdose Effects
There is no known antidote for overdose. Overdose treatment consists of supportive care, including monitoring vital signs. Dialysis is not likely to help remove the drug due to its strong attachment to proteins in the blood.
Therapeutic Class
Daclaxen belongs to the class of medicines used for treating Hepatitis C.
Storage Conditions
Store Daclaxen at room temperature below 30°C, away from light. Keep out of the reach of children.
Similar Brands of Daclatasvir (Tablet – 60mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Daclacee | Tablet | 60mg | Julphar Bangladesh Ltd. | 400.0 |
| Daclavir | Tablet | 60mg | Beacon Pharmaceuticals Ltd. | 400.0 |
| Dakla 60 | Tablet | 60mg | Healthcare Pharmaceuticals Ltd. | 400.0 |
| Dakovir-C 60 | Tablet | 60mg | Beximco Pharmaceuticals Ltd. | 400.0 |