Danazol
Form: Capsule
Strength: 200mg
Generic Name: Danazol
Company: The Ibn Sina Pharmaceutical Ind. Ltd.
MRP:৳ 38.0 (Strip=10)
Per Piece: ৳ 3.80
Is Antibiotic: No
Indications
Danazol is used to treat endometriosis, benign breast disease, heavy periods, enlarged breast tissue in men, and to thin the uterus lining before surgery.
Pharmacology
Danazol works by reducing certain hormones in the body, which helps slow down estrogen production. This leads to less hormone activity in the ovaries, reducing symptoms like pain and tissue growth. Danazol also affects how the body processes steroids and proteins, helping manage conditions like endometriosis and breast disease.
Dosage & Administration
Adults: Usually taken in 2 to 4 doses daily. For endometriosis, 200-800 mg per day for up to 9 months. For heavy periods, 100-200 mg per day for 3 months. For breast conditions, 100-400 mg per day for 3-6 months. For enlarged male breast tissue, 200-400 mg per day for up to 6 months.
Children: Not recommended.
Interaction
Danazol may affect blood sugar levels and interact with insulin. Danazol can also reduce the effectiveness of certain medications like birth control pills, migraine medicine, and blood pressure drugs. Danazol may increase the effects of medications like cyclosporine and some seizure treatments.
Contraindications
Danazol should not be used during pregnancy or breastfeeding, or by people with liver, kidney, or heart problems. Danazol is also not recommended for those with a history of blood clots, hormone-sensitive cancer, unexplained vaginal bleeding, or an allergy to the drug.
Side Effects
Possible side effects include nausea, dizziness, skin rashes, mood changes, anxiety, weight gain, headaches, irregular periods, voice changes, acne, and hair growth. Some people may also experience swelling, muscle pain, or changes in blood levels.
Pregnancy & Lactation
Danazol should not be taken during pregnancy as Danazol may affect a developing baby. Danazol is also not recommended for breastfeeding mothers, as Danazol can pass into breast milk.
Precautions & Warnings
Danazol should be used with caution in people with heart, liver, or kidney disease, diabetes, high blood pressure, migraines, or a history of blood clots. If signs of voice changes or unusual hair growth appear, the medicine should be stopped immediately.
Overdose Effects
There is limited data on overdose, but taking too much may cause severe hormonal side effects or worsen existing symptoms.
Therapeutic Class
Danazol belongs to the class of medicines that affect hormone levels.
Storage Conditions
Keep below 30°C, away from light and moisture. Keep out of reach of children.
Similar Brands of Danazol (Capsule – 200mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Danamet 200 | Capsule | 200mg | Eskayef Pharmaceuticals Ltd. | 38.0 |
| Dana | Capsule | 200mg | Delta Pharma Limited | 0.0 |
| Danzol 200 | Capsule | 200mg | Renata Limited | 38.0 |
| Dazol | Capsule | 200mg | Drug International Ltd. | 38.0 |