Dayprox
Form: Tablet
Strength: 600mg
Generic Name: Oxaprozin
Company: Eskayef Pharmaceuticals Ltd.
MRP:৳ 7.0 (Tablet)
Is Antibiotic: No
Indications
Dayprox is used to relieve symptoms of osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
Pharmacology
Dayprox is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing pain, inflammation, and fever. Dayprox is the potassium salt form of oxaprozin and is known to block the action of cyclooxygenase (COX-1 and COX-2), which are enzymes involved in making prostaglandins. Prostaglandins cause pain and inflammation, so by reducing them, Dayprox helps in controlling symptoms like pain and swelling.
Dosage & Administration
General Dosing Instructions: The dose should be as low as possible for the shortest time needed to manage symptoms. After the first dose, the dosage can be adjusted to fit the patient’s needs.
Osteoarthritis: Take 1200 mg (two 600 mg tablets) once a day.
Rheumatoid Arthritis: Take 1200 mg (two 600 mg tablets) once a day.
Note: For patients with low body weight or mild osteoarthritis, starting with 600 mg once a day may be enough. The maximum daily dose should not exceed 1200 mg.
Interaction
Taking aspirin with Dayprox can increase the risk of toxicity. Dayprox may also enhance the effects of blood thinners like warfarin and reduce the effectiveness of blood pressure medications like β-blockers and diuretics. Dayprox may also increase the risk of toxicity with drugs like methotrexate and lithium.
Contraindications
Dayprox should not be used by people with a history of peptic ulcers, allergies to NSAIDs, or certain heart surgery (CABG). Dayprox is also not suitable for perioperative pain management in CABG settings.
Side Effects
Common side effects include depression, drowsiness, confusion, rash, abdominal discomfort, nausea, constipation, and diarrhea. Serious side effects may include cardiovascular issues, GI bleeding, liver problems, kidney issues, allergic reactions, and severe skin reactions. If you experience any of these, contact a doctor immediately.
Pregnancy & Lactation
Dayprox is categorized as pregnancy category C (safe in some situations) but category D in the third trimester. Pregnant or breastfeeding women should consult a doctor before using Dayprox.
Precautions & Warnings
Dayprox should be used with caution in people with a history of ulcers, liver or kidney problems, and heart failure. Pregnant women should avoid using Dayprox in the third trimester, and Dayprox should be avoided by those with bleeding disorders. People with a history of alcohol use or smoking should be careful when using Dayprox.
Overdose Effects
Overdose symptoms include kidney failure, vomiting, and drowsiness. Treatment should be supportive, and multiple doses of charcoal may be needed to prevent delayed effects.
Therapeutic Class
Dayprox belongs to the class of drugs used for osteoarthritis and rheumatoid arthritis, as well as non-steroidal anti-inflammatory drugs (NSAIDs).
Storage Conditions
Store Dayprox at room temperature (25°C) and protect Dayprox from light.
Similar Brands of Oxaprozin (Tablet – 600mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Demarin | Tablet | 600mg | ACI Limited | 7.05 |