Demelon 1.5
Form: Capsule
Strength: 1.5mg
Generic Name: Rivastigmine
Company: Unimed Unihealth Pharmaceuticals Ltd.
MRP:৳ 23.0 (Strip=7)
Per Piece: ৳ 3.29
Is Antibiotic: No
Indications
Demelon 1.5 is used to treat mild to moderate Alzheimer’s disease and dementia associated with Parkinson’s disease.
Pharmacology
Demelon 1.5 is a medicine that affects the brain by blocking an enzyme that breaks down acetylcholine. This helps to increase the levels of acetylcholine, a substance important for memory and learning. Demelon 1.5 mainly works in the brain and not in other parts of the body.
Dosage & Administration
Adult & Elderly: Start with 1.5 mg twice a day. If the dose is well tolerated, Demelon 1.5 may be increased after two weeks to 3 mg, then 4.5 mg, and up to 6 mg twice a day if needed. The recommended dose is 3 mg to 6 mg twice a day. If treatment is stopped for more than a few days, restart at 1.5 mg twice a day.
Transdermal Patch: Apply a patch once a day. Start with a 4.6 mg patch. After 4 weeks, increase the dose to 9.5 mg if well tolerated. After 8 more weeks, the maximum dose of 13.3 mg can be used. If the patch treatment is interrupted for more than 3 days, restart with the 4.6 mg patch.
Interaction
Demelon 1.5 may increase the effects of certain muscle relaxants during anesthesia. Demelon 1.5 should not be used with other similar medicines. Demelon 1.5 does not interact with digoxin, warfarin, diazepam, or fluoxetine in healthy people. No effects were found on heart rhythm when used with digoxin.
Contraindications
Demelon 1.5 should not be used by people allergic to rivastigmine or other similar medicines.
Side Effects
Common side effects are stomach issues like nausea and vomiting, especially during the starting doses. Female patients may experience more side effects and weight loss compared to males.
Pregnancy & Lactation
There is not enough data on its safety during pregnancy, so Demelon 1.5 should only be used if absolutely necessary. Demelon 1.5 is known that rivastigmine passes into animal milk, but Demelon 1.5 is not clear if Demelon 1.5 does the same in humans. Demelon 1.5 should not be used while breastfeeding.
Precautions & Warnings
Be careful if you have heart conditions, lung problems, or stomach issues. Demelon 1.5 may cause problems in those with urinary blockages or a history of seizures. Pregnant and breastfeeding women, as well as those with kidney or mild liver problems, should use caution. Demelon 1.5 may also worsen certain symptoms in people with asthma or other breathing problems.
Overdose Effects
In most cases of overdose, there are no symptoms or mild symptoms like nausea, vomiting, and diarrhea. Serious symptoms may include slow heart rate or fainting. If overdose occurs, do not take more rivastigmine for 24 hours. In case of serious overdose, atropine may be used as an antidote.
Therapeutic Class
Demelon 1.5 belongs to drugs used to treat dementia.
Storage Conditions
Store in a cool, dry place away from light.
Similar Brands of Rivastigmine (Capsule – 1.5mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Benzenod 1.5 | Capsule | 1.5mg | General Pharmaceuticals Ltd. | 23.0 |
| Exelon 1.5 | Capsule | 1.5mg | Novartis (Bangladesh) Ltd. | 44.0 |
| Rivacap 1.5 | Capsule | 1.5mg | The Ibn Sina Pharmaceutical Ind. Ltd. | 12.0 |
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| Rivas 1.5 | Capsule | 1.5mg | Popular Pharmaceuticals Ltd. | 23.0 |
| Rivatig 1.5 | Capsule | 1.5mg | Square Pharmaceuticals Ltd. | 20.0 |
| Vastigro 1.5 | Capsule | 1.5mg | Incepta Pharmaceuticals Ltd. | 20.0 |