Dementa XR 7
Form: Capsule
Strength: 7mg
Generic Name: Memantine Hydrochloride
Company: Ziska Pharmaceuticals Ltd.
MRP:৳ 12.0 (Strip=10)
Per Piece: ৳ 1.20
Is Antibiotic: No
Indications
Dementa XR 7 is used to treat all types of Alzheimer’s dementia and may also be helpful for other types of dementia.
Pharmacology
Dementa XR 7 works by blocking certain receptors in the brain that are overactive in Alzheimer’s disease. This helps reduce the symptoms. Dementa XR 7 is well absorbed after oral intake and takes about 3-7 hours to reach its peak concentration in the body. Dementa XR 7 is mostly excreted unchanged in the urine. Food does not affect its absorption, and Dementa XR 7 is only slightly metabolized in the liver.
Dosage & Administration
Adults & Elderly: The recommended dose is 20 mg per day. To reduce the risk of side effects, the dose should be gradually increased over three weeks:
Week 1: 5 mg in the morning.
Week 2: 5 mg in the morning, 5 mg at night.
Week 3: 10 mg in the morning, 5 mg at night.
Week 4 and onwards: 10 mg in the morning, 10 mg at night.
If a dose is missed, take the next dose at the usual time. Do not take double doses.
In Renal Impairment: Patients with moderate kidney issues should take 10 mg per day. Severe kidney impairment should also follow the 10 mg dose per day.
In Hepatic Impairment: No adjustment needed for mild to moderate liver issues. Dementa XR 7 should not be used for severe liver impairment.
For Children: Dementa XR 7 is not recommended for children under 18 years due to lack of safety data.
Interaction
Dementa XR 7 may increase the effects of certain medications like L-dopa, dopaminergic drugs, and anticholinergics. Dementa XR 7 can reduce the effects of barbiturates and neuroleptics. Be careful when using Dementa XR 7 with antispasmodic agents like dantrolene or baclofen. Dementa XR 7 should not be used with amantadine, ketamine, dextromethorphan, phenytoin, cimetidine, ranitidine, and some other medications.
Contraindications
Dementa XR 7 should not be used in patients who are allergic to Dementa XR 7 or any of its ingredients.
Side Effects
The most common side effects (less than 2%) include hallucinations, confusion, dizziness, headache, and fatigue. Other less common effects include anxiety, muscle tension, vomiting, bladder infections, and increased sexual drive. Dementa XR 7 may also slightly increase the risk of seizures in patients with a history of epilepsy.
Pregnancy & Lactation
Dementa XR 7 is in Pregnancy Category B, meaning that Dementa XR 7 has not been fully studied in pregnant women. Dementa XR 7 should only be used if the potential benefit outweighs the risks. Dementa XR 7 is unknown whether Dementa XR 7 passes into breast milk, so caution is advised when nursing.
Precautions & Warnings
Caregivers should ensure proper administration and dose adjustments. Regular kidney function checks are advised for patients with kidney problems. Dementa XR 7 has not been tested thoroughly in patients with seizures. Memantine does not cause cancer or affect fertility.
Dementa XR 7 may affect reaction times, so patients should be cautious when driving or operating machinery.
Overdose Effects
No specific overdose information is available.
Drug Classes
N/A
Storage Conditions
Store in a cool, dry place, away from light. Keep out of reach of children.
Similar Brands of Memantine Hydrochloride (Capsule – 7mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Remtin XR 7 | Capsule | 7mg | Incepta Pharmaceuticals Ltd. | 12.0 |