Depodrol
Form: Tablet
Strength: 16mg
Generic Name: Methylprednisolone
Company: Opsonin Pharma Limited
MRP:৳ 20.0 (Tablet)
Is Antibiotic: No
Indications
Depodrol is used to treat various conditions such as:
- Endocrine disorders like Adrenal Insufficiency, Adrenal Hyperplasia, Thyroiditis, and Hypercalcemia from cancer.
- Rheumatic disorders like Rheumatoid Arthritis, Juvenile Rheumatoid Arthritis, and Osteoarthritis-related conditions.
- Collagen diseases like Lupus, Dermatomyositis, and Acute Rheumatic Heart Disease.
- Severe skin conditions like Bullous Dermatitis and Psoriasis.
- Allergies like Rhinitis, Asthma, and Drug Reactions.
- Eye conditions like Allergic Corneal Ulcers and Conjunctivitis.
- Respiratory diseases such as Sarcoidosis and Pneumonitis.
- Blood disorders like Thrombocytopenia and Hemolytic Anemia.
- Some types of cancers like Leukemia and Lymphoma.
- Edematous conditions like Nephrotic Syndrome and protein-related kidney issues.
- Digestive diseases like Ulcerative Colitis.
- Neurological conditions like Multiple Sclerosis.
Pharmacology
Depodrol is a strong anti-inflammatory drug that suppresses the immune system. Depodrol works by attaching to specific receptors in cells, which then help control the body’s response to inflammation and immune functions. Depodrol affects the kidney, metabolism, muscles, heart, immune system, and nervous system.
Dosage & Administration
The typical dose is between 2-48 mg daily, depending on the disease.
- For anti-inflammatory or immunosuppressive treatment, doses can range from 4-48 mg per day.
- For severe conditions like Multiple Sclerosis, 160 mg per day is used initially, followed by a lower dose.
- If tapering off, the dosage should be reduced slowly to avoid withdrawal symptoms.
Interaction
Depodrol interacts with several drugs, including:
- Medications like Erythromycin and Ketoconazole can slow down its breakdown.
- Estrogen-containing drugs may increase its effects.
- Depodrol may affect blood thinners, so their dosage may need to be adjusted.
Contraindications
Depodrol should not be used in patients with systemic fungal infections or those allergic to any of its components.
Side Effects
Side effects can range from mild to serious, and include:
- Fluid retention, weight gain, high blood pressure.
- Muscle weakness, headaches, mood swings, and sleep problems.
- Long-term use may cause issues like cataracts, stomach ulcers, and growth problems in children.
Pregnancy & Lactation
If pregnant or breastfeeding, contact your doctor. Depodrol is not fully studied in nursing mothers and should be used cautiously during pregnancy if the benefit outweighs the risk.
Precautions & Warnings
Be cautious if you have a thyroid problem, cirrhosis, or eye herpes. Regular monitoring is needed during long-term treatment.
Overdose Effects
Overdose is rare, but Depodrol can cause symptoms like electrolyte imbalances. No specific antidote exists, so treatment focuses on managing symptoms.
Therapeutic Class
Depodrol belongs to the class of Glucocorticoids.
Storage Conditions
Store Depodrol in a cool, dry place, away from light, and out of reach of children.
Similar Brands of Methylprednisolone (Tablet)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Depodrol 4 | Tablet | 4mg | Opsonin Pharma Limited | 5.0 |
| Depodrol 8 | Tablet | 8mg | Opsonin Pharma Limited | 10.0 |
| Depomed 16 | Tablet | 16mg | Drug International Ltd. | 20.0 |
| Depomed | Tablet | 2mg | Drug International Ltd. | 3.0 |
| Depomed 2 | Tablet | 2mg | Drug International Ltd. | 3.0 |
| Depomed 4 | Tablet | 4mg | Drug International Ltd. | 6.0 |
| Depomed 8 | Tablet | 8mg | Drug International Ltd. | 10.0 |
| Melpred | Tablet | 16mg | Pharmasia Ltd. | 22.0 |
| Melpred 2 | Tablet | 2mg | Pharmasia Ltd. | 3.0 |
| Melpred | Tablet | 4mg | Pharmasia Ltd. | 6.0 |
| Melpred | Tablet | 8mg | Pharmasia Ltd. | 11.0 |
| Mepcort 16 | Tablet | 16mg | Globe Pharmaceuticals Ltd. | 18.0 |
| Mepcort 4 | Tablet | 4mg | Globe Pharmaceuticals Ltd. | 5.0 |
| Mepcort 8 | Tablet | 8mg | Globe Pharmaceuticals Ltd. | 10.0 |
| Methigic 16 | Tablet | 16mg | Square Pharmaceuticals Ltd. | 20.5 |
| Methigic 2 | Tablet | 2mg | Square Pharmaceuticals Ltd. | 3.0 |
| Methigic 4 | Tablet | 4mg | Square Pharmaceuticals Ltd. | 5.0 |
| Methigic 8 | Tablet | 8mg | Square Pharmaceuticals Ltd. | 10.5 |
| Methipred 16 | Tablet | 16mg | General Pharmaceuticals Ltd. | 20.06 |
| Methipred 2 | Tablet | 2mg | General Pharmaceuticals Ltd. | 3.01 |
| Methipred 4 | Tablet | 4mg | General Pharmaceuticals Ltd. | 5.75 |
| Methipred 8 | Tablet | 8mg | General Pharmaceuticals Ltd. | 11.0 |
| Methsolon 4 | Tablet | 4mg | Incepta Pharmaceuticals Ltd. | 6.0 |
| Predixa 16 | Tablet | 16mg | Unimed Unihealth Pharmaceuticals Ltd. | 24.0 |
| Predixa 4 | Tablet | 4mg | Unimed Unihealth Pharmaceuticals Ltd. | 6.0 |
| Predixa 8 | Tablet | 8mg | Unimed Unihealth Pharmaceuticals Ltd. | 12.0 |
| Solupred 16 | Tablet | 16mg | Ziska Pharmaceuticals Ltd. | 19.5 |
| Solupred 2 | Tablet | 2mg | Ziska Pharmaceuticals Ltd. | 3.0 |
| Solupred 4 | Tablet | 4mg | Ziska Pharmaceuticals Ltd. | 5.0 |
| Solupred 8 | Tablet | 8mg | Ziska Pharmaceuticals Ltd. | 9.5 |