Dormitol Inj
Form: Injection
Strength: 15mg/3ml
Generic Name: Midazolam
Company: Square Pharmaceuticals Ltd.
MRP:৳ 120.37 (Injection)
Is Antibiotic: No
Indications
Dormitol Inj is used for short-term treatment of insomnia and for sedation before surgical or diagnostic procedures.
Pharmacology
Dormitol Inj works through the neurotransmitter gamma-aminobutyric acid (GABA), which helps relax the muscles, sedate the body, and cause sleep, anesthesia, and amnesia. Dormitol Inj enhances GABA’s effect by increasing the frequency of chloride channel openings in the central nervous system, particularly in the heart and muscles.
Dosage & Administration
Oral dosage:
For adults: 7.5-15 mg daily.
For elderly or weak patients: 7.5 mg daily.
For premedication: 15 mg should be taken 30-60 minutes before the procedure.
Intravenous administration:
For endoscopic or cardiovascular procedures in healthy adults: 2.5 mg. For severely ill or elderly patients: 1-1.5 mg.
For induction of anesthesia: 10-15 mg.
Intramuscular administration:
For adults: 0.07-0.1 mg/kg body weight (usually 5 mg).
For children: 0.15-0.20 mg/kg.
For elderly or weak patients: 0.025-0.05 mg/kg.
Rectal administration for children:
0.35-0.45 mg/kg 20-30 minutes before anesthesia.
Interaction
Dormitol Inj can increase the sedative effects of other medications like neuroleptics, tranquilizers, antidepressants, sleep aids, painkillers, anesthetics, antipsychotics, anti-anxiety drugs, anti-epileptic drugs, and sedative antihistamines.
Contraindications
Dormitol Inj should not be used by people with severe breathing problems, severe liver problems, myasthenia gravis, sleep apnea, or a known allergy to benzodiazepines or any of its components.
Side Effects
At the start of treatment, drowsiness, confusion, fatigue, headache, and muscle weakness may occur but usually disappear after a few doses. After IV or IM use, changes in vital signs like breathing problems, low blood pressure, and heart rate changes may occur.
Pregnancy & Lactation
Dormitol Inj should be avoided during pregnancy unless no other options are available. Since Dormitol Inj passes into breast milk, Dormitol Inj should not be used by breastfeeding mothers.
Precautions & Warnings
Dormitol Inj should be given very slowly through IV.
Overdose Effects
Overdosing may cause coma, loss of reflexes, breathing problems, and heart issues. These can be treated with the benzodiazepine antagonist flumazenil.
Therapeutic Class
Dormitol Inj belongs to the class of benzodiazepine hypnotics and sedatives.
Storage Conditions
Store in a cool, dry place, away from light and moisture. Keep out of reach of children.
Similar Brands of Midazolam (Injection – 15mg/3ml)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Anquil Inj | Injection | 15mg/3ml | General Pharmaceuticals Ltd. | 120.0 |
| Dormax | Injection | 15mg/3ml | Aristopharma Limited | 150.0 |
| Hypnofast | Injection | 15mg/3ml | Incepta Pharmaceuticals Ltd. | 150.0 |
| Midolam | Injection | 15mg/3ml | Opsonin Pharma Limited | 75.5 |
| Midzo IM/IV | Injection | 15mg/3ml | Renata Limited | 75.0 |
| Milam Inj | Injection | 15mg/3ml | Eskayef Pharmaceuticals Ltd. | 120.0 |