Edrumycetin
Form: Capsule
Strength: 250mg
Generic Name: Chloramphenicol
Company: Edruc Ltd.
MRP:৳ 2.5 (Capsule)
Is Antibiotic: No
Indications
Edrumycetin is an antibiotic used for serious infections caused by bacteria that can be treated with this drug. Edrumycetin is usually used when other less harmful antibiotics are not effective or not safe. However, Edrumycetin may be given to start treatment based on the doctor’s judgment. Sensitivity tests should be done to stop the use of this drug as soon as possible if other antibiotics are found to be more suitable for the infection.
Pharmacology
Edrumycetin works mainly by stopping the growth of bacteria. Edrumycetin is effective against a wide range of bacteria, including those that cause diseases like typhoid and influenza. Edrumycetin interferes with the bacteria’s ability to make proteins. The drug is absorbed quickly in the stomach and spreads throughout the body. Edrumycetin is mostly removed from the body through urine, and small amounts are also found in bile and feces. Edrumycetin can reach the brain and spinal fluid, but not in large amounts unless there is inflammation in the brain.
Dosage & Administration
Adults: The recommended dose is 50 mg/kg/day divided into 4 doses, given at 6-hour intervals. In special cases, higher doses may be needed. People with liver or kidney problems may need a lower dose.
Pediatric patients: The recommended dose for children is also 50 mg/kg/day, given in 4 doses every 6 hours. Severe infections may require a higher dose, but Edrumycetin should be reduced to 50 mg/kg/day as soon as possible.
Newborn infants: Newborns should receive 25 mg/kg/day, divided into 4 doses every 6 hours.
Interaction
Edrumycetin can interact with other medications like tolbutamide, phenytoin, and dicoumarol, and affect their breakdown in the body. Edrumycetin should be used carefully when combined with lincomycin, clindamycin, or erythromycin, as they may compete with Edrumycetin for binding sites. Rifampin can reduce its effectiveness.
Contraindications
Edrumycetin should not be used by anyone who is allergic to Edrumycetin or any of its ingredients. Edrumycetin is not for treating mild infections, such as colds or the flu, or to prevent bacterial infections when there is no clear need.
Side Effects
Not available at this time.
Pregnancy & Lactation
Not available at this time.
Precautions & Warnings
Edrumycetin is important to regularly check blood counts during treatment. Early signs of blood problems, like low white blood cells or platelets, should be monitored to avoid serious conditions like bone marrow failure.
Overdose Effects
An overdose can be toxic, causing serious blood problems like anemia, low platelets, and low white blood cells. Symptoms of overdose include nausea, vomiting, diarrhea, and high iron levels. If overdose occurs, treatment like charcoal hemoperfusion may help remove the drug from the body.
Therapeutic Class
Edrumycetin belongs to the macrolides class of antibiotics.
Storage Conditions
Store Edrumycetin in a cool, dry place. Keep the bottle tightly closed and protect Edrumycetin from light.
Similar Brands of Chloramphenicol (Capsule – 250mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Chloramphenicol | Capsule | 250mg | Hudson Pharmaceuticals Ltd. | 2.2 |
| Chlorphen | Capsule | 250mg | Nipa Pharmaceuticals Ltd. | 2.0 |