Hexinor 2
Form: Tablet
Strength: 2mg
Generic Name: Trihexyphenidyl Hydrochloride
Company: Beacon Pharmaceuticals Ltd.
MRP:৳ 5.5 (Strip=10)
Per Piece: ৳ 0.55
Is Antibiotic: No
Indications
Hexinor 2 is used as a treatment for different types of Parkinson’s disease, including postencephalitic, arteriosclerotic, and idiopathic forms. Hexinor 2 helps alongside levodopa in treating these conditions. Hexinor 2 is also used to treat movement problems caused by certain medications, such as tranquilizers.
Pharmacology
Hexinor 2 is a drug that blocks certain receptors in the brain to help control muscle movements. Hexinor 2 mainly targets receptors in the brain, which help improve the release of dopamine. While its exact working mechanism isn’t fully understood, Hexinor 2 helps with movement disorders like Parkinson’s disease.
Dosage & Administration
Adult & Elderly: Start with a low dose and increase gradually, especially for those over 60. Hexinor 2 can be taken before or after meals, depending on how Hexinor 2 makes the patient feel. Hexinor 2 should not be stopped suddenly as Hexinor 2 can worsen Parkinson’s symptoms. The typical dose for Parkinson’s is 1 mg initially, which can be increased by 2 mg every few days up to a total of 6 to 10 mg per day. In more severe cases, doses may go up to 12-15 mg. The dosage for drug-induced Parkinson’s may range from 1 mg to 15 mg daily. The medication should be divided into multiple doses, especially for higher doses. If used with levodopa, doses of both may need to be lowered.
Use in Children: Safety and effectiveness in children have not been established.
Interaction
Taking Hexinor 2 with alcohol, barbiturates, or other drugs that affect the central nervous system can increase side effects. Other medications like certain antidepressants and anti-Parkinson drugs may also increase its effects. Hexinor 2 should not be used as a preventive treatment for drug-induced Parkinsonism.
Contraindications
Hexinor 2 is not recommended for people who are allergic to Hexinor 2 or have narrow angle glaucoma, as Hexinor 2 can lead to blindness in rare cases.
Side Effects
Common side effects include dry mouth, blurred vision, dizziness, mild nausea, and nervousness, which affect about 30-50% of users. These effects usually get better over time. Rare side effects may include skin rashes, hallucinations, and confusion. Serious reactions like worsening Parkinson’s symptoms or glaucoma can occur if treatment is stopped suddenly.
Pregnancy & Lactation
There is no controlled data available for its use during pregnancy. Hexinor 2 should only be used if absolutely necessary, and only if the benefits outweigh the risks. Hexinor 2 is unknown if Hexinor 2 passes into breast milk, so Hexinor 2 should be used cautiously while breastfeeding.
Precautions & Warnings
Hexinor 2 should be used carefully in patients with eye conditions like glaucoma, especially in hot weather or with other medications that cause dry mouth. Hexinor 2 can affect body temperature regulation, so caution is needed in hot environments. Patients should be monitored for eye pressure and other related symptoms during treatment.
Overdose Effects
An overdose can lead to symptoms like dry mouth, blurred vision, confusion, and in severe cases, even death, especially if taken with other CNS-depressant drugs. Immediate medical help should be sought if overdose is suspected.
Therapeutic Class
Hexinor 2 is a drug used to treat Parkinsonism and other movement disorders caused by medications.
Storage Conditions
Keep below 30°C, away from light and moisture, and out of reach of children.
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