Navacef
Form: Pediatric Drops
Generic Name: Cefaclor
Company: Navana Pharmaceuticals Ltd.
MRP:৳ 135.0 (15ml bot)
Is Antibiotic: Yes
Indications
Navacef is used to treat the following infections:
- Respiratory infections like pneumonia and bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae, and Streptococcus pyogenes.
- Ear infections (otitis media) caused by Streptococcus pneumoniae, Haemophilus influenzae, Staphylococci, and Streptococcus pyogenes.
- Throat infections (pharyngitis and tonsillitis) caused by Streptococcus pyogenes.
- Urinary infections (like pyelonephritis and cystitis) caused by Escherichia coli, Proteus mirabilis, Klebsiella spp., and coagulase-negative Staphylococci.
- Skin infections caused by Staphylococcus aureus and Streptococcus pyogenes.
Pharmacology
Navacef is a second-generation antibiotic that works against a broad range of bacteria. Navacef is effective against Streptococci, Staphylococci, and other bacteria like Escherichia coli, Haemophilus influenzae, and Klebsiella species. Navacef is also helpful in treating infections in the nose and throat caused by Streptococci.
Dosage & Administration
Adults: The usual dose is 250 mg every 8 hours. For more severe infections, the dose may be doubled to a maximum of 4 g per day. For throat infections, treatment should last at least 10 days.
Children: For children over 1 month, the usual dose is 20 mg per kg per day, divided into 3 doses. For serious infections, the dose can go up to 40 mg per kg per day, with a maximum of 1 g per day.
For infants (less than 1 month): Safety has not been established.
For renal impairment: Dose adjustments may be necessary for patients with kidney problems.
For patients on dialysis: A loading dose of 250 mg to 1 g is recommended before dialysis, with maintenance doses after dialysis.
Interaction
Navacef may cause false-positive urine glucose tests. When taken with blood thinners (like warfarin), Navacef may increase the blood-thinning effect, so regular monitoring is advised.
Contraindications
Navacef is not recommended for patients who are allergic to cephalosporin antibiotics.
Side Effects
Common side effects include diarrhea, nausea, and vomiting. Rare side effects include liver problems, fever, abdominal pain, and kidney issues.
Pregnancy & Lactation
Navacef should only be used during pregnancy if necessary. Small amounts may pass into breast milk, so caution is advised when used by breastfeeding women.
Precautions & Warnings
Navacef should not be used without a proven bacterial infection. Prolonged use can lead to resistant bacteria. Use with caution in patients with a history of allergies, especially to penicillins or other antibiotics.
Overdose Effects
Overdose symptoms may include nausea, vomiting, stomach pain, and diarrhea.
Therapeutic Class
Second-generation cephalosporin antibiotics.
Storage Conditions
Store at room temperature, away from light. After mixing, the suspension should be used within 7 days at room temperature or 14 days in the refrigerator.
Similar Brands of Cefaclor (Pediatric Drops – None)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Ceflon | Pediatric Drops | None | Eskayef Pharmaceuticals Ltd. | 135.0 |
| Cefticlor | Pediatric Drops | None | Renata Limited | 125.0 |
| CFL | Pediatric Drops | None | Sharif Pharmaceuticals Ltd. | 125.37 |
| Loracef | Pediatric Drops | None | Square Pharmaceuticals Ltd. | 135.0 |
| Oticef PD | Pediatric Drops | None | Alco Pharma Limited | 125.38 |
| Oticlor | Pediatric Drops | None | Incepta Pharmaceuticals Ltd. | 135.0 |
| Uniclor | Pediatric Drops | None | Leon Pharmaceuticals Ltd. | 125.37 |