Omaglip
Form: Tablet
Strength: 12.5mg
Generic Name: Omarigliptin
Company: Navana Pharmaceuticals Ltd.
MRP:৳ 80.0 (Box=4)
Per Piece: ৳ 20.00
Is Antibiotic: No
Indications
Omaglip is used to treat adults with type 2 diabetes.
Pharmacology
Omaglip is a long-acting medicine that works by blocking the DPP-4 enzyme. DPP-4 breaks down hormones that help lower blood sugar. These hormones, called incretins, help reduce blood sugar levels after eating by increasing insulin and decreasing glucagon. By blocking DPP-4, Omaglip helps incretin hormones work better to control blood sugar.
Dosage & Administration
Route of administration: Take Omaglip by mouth.
Recommended dosage: The usual dose is 25 mg once a week, either alone or along with other medicines to control blood sugar. If a dose is missed, take Omaglip as soon as possible, then continue with the regular weekly schedule. Never take two doses at once.
Renal impairment: For patients with severe kidney problems or those on dialysis, the dose should be reduced to 12.5 mg once a week. This is based on kidney function.
Use in children and adolescents: Its safety and effectiveness for children and adolescents have not been established.
Interaction
Omaglip may interact with medicines like metformin, glimepiride, oral contraceptives, and atorvastatin. Caution is needed when used with other anti-diabetic drugs (like insulin or sulfonylureas) as they may cause low blood sugar. Omaglip should also be used carefully with drugs that increase the risk of low blood sugar (such as beta-blockers, salicylic acid, and monoamine oxidase inhibitors). Blood sugar should be monitored when used with drugs that reduce the effect of low blood sugar (like adrenaline or thyroid hormones).
Contraindications
Omaglip is not suitable for people who are allergic to Omaglip or any of its ingredients. Omaglip should not be used in patients with severe ketosis, diabetic coma, or precoma, or in type 1 diabetes patients. Omaglip is also not recommended for severe infections, before or after surgery, or in patients with serious trauma.
Side Effects
The side effects are usually mild and well-tolerated. Common side effects include a sore throat, low blood sugar, constipation, diarrhea, stomach issues, and skin problems.
Pregnancy & Lactation
Omaglip has not been tested in pregnant women. Omaglip should only be used if the benefits outweigh the risks to the baby. Breastfeeding mothers should avoid using Omaglip.
Precautions & Warnings
Omaglip should be used carefully in patients who may develop low blood sugar, such as those with pituitary or adrenal problems, poor nutrition, lack of food, excessive alcohol use, or the elderly. Special care should also be taken for people working at heights or driving vehicles.
Overdose Effects
There is no information available on overdosing with Omaglip. If overdose occurs, supportive care should be given.
Therapeutic Class
Omaglip belongs to the class of medicines called Dipeptidyl Peptidase-4 (DPP-4) inhibitors.
Storage Conditions
Store Omaglip in a cool (below 30°C), dry place away from light. Keep Omaglip out of reach of children.
Similar Brands of Omarigliptin (Tablet – 12.5mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Marzev 12.5 | Tablet | 12.5mg | ACI Limited | 80.0 |
| Omaglo | Tablet | 12.5mg | Ziska Pharmaceuticals Ltd. | 80.0 |
| Omari 12.5 | Tablet | 12.5mg | The ACME Laboratories Ltd. | 70.0 |
| Wikitin 12.5 | Tablet | 12.5mg | Aristopharma Limited | 75.0 |