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Kevil

Form: Suspension

Strength: 5mg/5ml

Generic Name: Loratadine

Company: Kemiko Pharmaceuticals Ltd.

MRP:৳ 30.9   (60ml bot)

Is Antibiotic: No

Indications

Kevil is used to relieve symptoms of seasonal and perennial allergic rhinitis, and skin allergies like chronic hives. Kevil helps with symptoms like sneezing, runny nose, itchy eyes, and burning eyes. Kevil quickly relieves nasal and eye symptoms after taking Kevil. Kevil is also used for idiopathic urticaria (hives). For children over 2 years, Kevil is used for seasonal allergic rhinitis and allergic skin conditions like hives or nettlerash.

Pharmacology

This tablet contains Loratadine, a non-sedative antihistamine that helps fight allergies. Kevil works by blocking histamine H1 receptors in the body, preventing allergic reactions. Loratadine is a long-acting medication that works well and doesn’t cause drowsiness, making Kevil effective with just one dose per day.

Dosage & Administration

Adults and children over 12 years: One tablet once daily, usually in the morning or whenever symptoms occur.

Children 2-12 years: For those weighing over 30 kg, one tablet once daily. For those below 30 kg, half a tablet once daily.

Children under 2 years: Kevil is not recommended for children below 2 years as safety and effectiveness are not established.

Interaction

There are no reports of dangerous interactions with other medicines. Unlike many antihistamines, Loratadine doesn’t cause problems when taken with alcohol. However, taking Kevil with medications like Cimetidine, Erythromycin, or Ketoconazole, which affect liver enzymes, can increase the levels of Loratadine in the body. No adverse effects have been reported in this case.

Contraindications

Kevil is contraindicated in patients who are allergic or sensitive to any of its components.

Side Effects

Kevil is generally well tolerated. Clinical studies show that side effects like drowsiness and dry mouth are rare and similar to those of a placebo. Loratadine does not affect driving or mental performance.

Pregnancy & Lactation

There is not enough information on Loratadine use during pregnancy, so Kevil is not recommended. Loratadine does pass into breast milk in small amounts, so Kevil should not be used by nursing mothers.

Precautions & Warnings

Kevil should be used with caution in patients with liver or kidney problems (eGFR <30 ml/min).

Overdose Effects

If overdosed, symptoms like drowsiness, fast heart rate, and headache may occur in adults. Children might experience extrapyramidal symptoms and palpitations. In case of overdose, general supportive treatment should be started right away. Activated charcoal can be used, and if vomiting is necessary, Kevil can be induced or gastric lavage can be performed.

Therapeutic Class

Non-sedating antihistamines

Storage Conditions

Store in a dry place, away from light and heat. Keep out of the reach of children.

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