Linax E 5/10
Form: tablet
Strength: 10mg+5mg
Generic Name: Empagliflozin+Linagliptin
MRP:৳ 20.0 (Strip=10)
Per Piece: ৳ 2.00
Is Antibiotic: No
Indications
Linax E 5/10 is used with diet and exercise to help control blood sugar in adults with type 2 diabetes.
Pharmacology
Linagliptin blocks an enzyme called DPP-4, which helps increase the levels of hormones that control blood sugar. This leads to more insulin being released when blood sugar is high and reduces the amount of glucagon, which helps lower blood sugar. Empagliflozin is a medication that blocks SGLT2, which is responsible for reabsorbing glucose from the kidneys. By blocking this, Linax E 5/10 helps the kidneys remove excess glucose from the body through urine.
Dosage & Administration
Recommended dose: 10 mg Empagliflozin and 5 mg Linagliptin once daily, in the morning, with or without food.
Increased dose: The dose can be increased to 25 mg Empagliflozin and 5 mg Linagliptin once daily if needed.
Renal impaired patients: Check kidney function before starting this medicine. Do not use if kidney function is below 45 mL/min/1.73 m2. Stop the medicine if kidney function drops below this level.
Interaction
Diuretics: Taking this medicine with diuretics may cause increased urination and dehydration.
Insulin: Using this medicine with insulin can increase the risk of low blood sugar.
Rifampin: Rifampin may reduce the effectiveness of Linagliptin.
Urine glucose test: This medicine can cause a positive urine glucose test.
1,5-AG Test: This medicine may interfere with the 1,5-AG test used to check blood sugar control.
Contraindications
Linax E 5/10 should not be used in patients with severe kidney problems, end-stage kidney disease, or those on dialysis. Also, Linax E 5/10 should not be used if there is a history of allergic reactions to Linagliptin or Empagliflozin.
Side Effects
Some side effects may include inflammation of the pancreas, ketoacidosis (a serious condition), low blood pressure, urinary tract infections, low blood sugar (when used with insulin), and serious infections like Fournier’s gangrene. Other side effects may include genital infections, joint pain, and skin reactions.
Pregnancy & Lactation
This medicine is not recommended during the second and third trimesters of pregnancy. Linax E 5/10 is important to control blood sugar levels during pregnancy to avoid risks to both the mother and the baby.
Precautions & Warnings
Be cautious if you have conditions like pancreatitis, low blood pressure, kidney problems, urinary tract infections, or a risk of low blood sugar. There have been reports of serious side effects like acute pancreatitis and kidney problems in people taking this medicine.
Overdose Effects
If you overdose on this medicine, contact a Poison Control Center immediately. Treatment will depend on the symptoms, and the medicine may not be easily removed by dialysis.
Therapeutic Class
Linax E 5/10 is classified as a Sodium-glucose Cotransporter-2 (SGLT2) Inhibitor.
Storage Conditions
Store the medicine below 30°C, away from light and moisture. Keep Linax E 5/10 out of the reach of children.
Similar Brands of Empagliflozin+Linagliptin (tablet)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Emaglin-L 10/5 | tablet | 10mg+5mg | None | 30.0 |
| Emaglin-L 10/5 | tablet | 10mg+5mg | None | 30.0 |
| Emaglin-L 25/5 | tablet | 25mg+5mg | None | 40.0 |
| Emaglin-L 25/5 | tablet | 25mg+5mg | None | 40.0 |
| Emparol-L 10/5 | tablet | 10mg+5mg | None | 30.0 |
| Emparol-L 25/5 | tablet | 25mg+5mg | None | 40.0 |
| Linax E 5/25 | tablet | 25mg+5mg | None | 30.0 |