Refain TR
Form: Capsule
Strength: 100mg
Generic Name: Diclofenac Sodium
Company: Monicopharma Limited
MRP:৳ 3.0 (Capsule)
Is Antibiotic: No
Indications
Refain TR is used to treat different types of arthritis, including inflammation and wear-and-tear forms of rheumatism, polyarthritis, ankylosing spondylitis, osteoarthritis, gout, and peri-articular rheumatic disorders.
Refain TR is also used for sprains, bruises, dislocations, fractures, soft tissue injuries, and recovery from surgery.
In gynecology, Refain TR is used for pain during menstruation, after episiotomy, and conditions like adnexitis, endometritis, salpingitis, and mastitis.
In ear, nose, and throat treatments, Refain TR helps prevent pain, swelling, and inflammation before surgery.
In dentistry, Refain TR is used for post-surgical and post-trauma pain, swelling, and inflammation.
Refain TR is also used to prevent and treat pain, inflammation, and swelling after surgery in the urogenital tract, or in cases of kidney and bile-related pain.
Pharmacology
Refain TR is a strong anti-inflammatory drug that also relieves pain and reduces fever. Refain TR works by stopping the production of prostaglandins, substances that cause inflammation and pain in the body. Refain TR is quickly absorbed after being taken, especially when taken with or after food, and reaches its peak effect in about 2 hours. Refain TR is mostly bound to plasma proteins and is metabolized in the liver.
Dosage & Administration
Diclofenac FC Tablet: For adults, 75-150 mg daily in 2 to 3 doses, preferably after food. The dose may be lowered for long-term use.
Diclofenac SR Tablet: For adults, 1 tablet daily, taken whole with water, preferably during meals. The dose may be increased to 150 mg if needed. For children, 1-3 mg per kg of body weight daily in divided doses. Elderly patients should use the lowest effective dose.
Diclofenac Dispersible Tablet: For adults, 2-3 tablets daily, not exceeding 150 mg. In milder cases, 2 tablets may be enough. Children may use Refain TR for juvenile rheumatoid arthritis at a dose of 1-3 mg per kg of body weight. Dissolve the tablet in half a glass of water before swallowing.
Diclofenac TR Capsule: One capsule daily, preferably after meals.
Diclofenac Suppository: For adults, 50 mg, 2-3 times daily. Maximum daily dose is 150 mg.
Diclofenac Injection: For adults, 1 ampoule daily. In serious cases, the dose can be increased to 2 ampoules daily.
Diclofenac Gel: Apply 2-4 g to the affected area 3-4 times daily. Rub Refain TR in lightly. Refain TR can be used with other forms of Diclofenac treatment.
Interaction
Refain TR may increase levels of lithium and digoxin in the blood.
Refain TR can increase the risk of bleeding when taken with anticoagulants.
Refain TR does not affect the action of oral diabetes medications.
Refain TR may cause kidney problems when taken with cyclosporine.
Taking Refain TR with methotrexate within 24 hours may increase toxicity.
Convulsions may occur if Refain TR is taken with quinolone antibiotics, so caution is needed.
Refain TR should not be used with other NSAIDs or steroids unless directed by a doctor, as this can increase side effects.
Contraindications
Refain TR should not be used by people allergic to any of its ingredients. Refain TR is also not recommended for people with peptic ulcers or asthma triggered by non-steroidal anti-inflammatory drugs (NSAIDs).
Refain TR should not be used under airtight dressings for the gel form.
Side Effects
Refain TR is usually well tolerated. Side effects are rare and mild, like stomach pain, nausea, diarrhea, dizziness, or headache. Skin reactions such as rash and swelling can also occur. The gel may cause skin irritation, redness, or rash.
Pregnancy & Lactation
Refain TR should only be used during pregnancy if absolutely necessary and at the lowest effective dose. Refain TR is not recommended during the first trimester. A small amount may pass into breast milk, but Refain TR is unlikely to affect the baby.
Precautions & Warnings
Refain TR should be used with caution in people who have a history of ulcers or gastrointestinal bleeding. Elderly patients should be monitored closely. The gel should not come in contact with the eyes or mucous membranes, and hands should be washed after use.
Overdose Effects
Not available.
Therapeutic Class
Refain TR is used for osteoarthritis, rheumatoid arthritis, and as a non-steroidal anti-inflammatory drug (NSAID).
Storage Conditions
Store in a cool, dry place, away from light. Keep below 30°C and out of the reach of children.
Similar Brands of Diclofenac Sodium (Capsule – 100mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Aid 100 TR | Capsule | 100mg | Premier Pharmaceuticals | 3.0 |
| Alcofen SR | Capsule | 100mg | Gaco Pharmaceuticals(G.A Company Ltd) | 0.0 |
| Alterin TR | Capsule | 100mg | Euro Pharma Ltd. | 3.0 |
| Anodyne SR | Capsule | 100mg | The Ibn Sina Pharmaceutical Ind. Ltd. | 4.0 |
| Apain TR | Capsule | 100mg | Kemiko Pharmaceuticals Ltd. | 3.0 |
| C-Fenac TR | Capsule | 100mg | Chemist Laboratories Ltd. | 4.0 |
| Clofenac TR | Capsule | 100mg | Square Pharmaceuticals Ltd. | 4.02 |
| Clonac TR | Capsule | 100mg | Somatec Pharmaceuticals Ltd. | 3.01 |
| Cosfenac SR | Capsule | 100mg | Cosmo Pharma Laboratories Ltd. | 3.0 |
| Diclo-TR | Capsule | 100mg | Apollo Pharmaceutical Laboratories Ltd. | 3.0 |
| Diclofenac TR | Capsule | 100mg | Albion Laboratories Ltd. | 3.0 |
| Diclonac TR | Capsule | 100mg | Ziska Pharmaceuticals Ltd. | 4.0 |
| Diclora TR | Capsule | 100mg | Marksman Pharmaceutical Ltd. | 3.0 |
| Diclovir 100 SR | Capsule | 100mg | Virgo Pharmaceuticals Ltd. | 3.0 |
| Dilock TR | Capsule | 100mg | Bristol Pharma Ltd. | 0.0 |
| Dinac TR | Capsule | 100mg | Navana Pharmaceuticals Ltd. | 3.0 |
| Dix TR | Capsule | 100mg | Apex Pharma Ltd. | 2.8 |
| DSR SR | Capsule | 100mg | NIPRO JMI Pharma Limited | 3.0 |
| Edifenac TR | Capsule | 100mg | Edruc Ltd. | 3.0 |
| Erdon TR | Capsule | 100mg | Aristopharma Limited | 4.0 |
| Geofenac 100 TR | Capsule | 100mg | Bristol Pharma Ltd. | 3.0 |
| Hipain TR | Capsule | 100mg | Pharmik Laboratories Ltd. | 3.0 |
| Jefenac TR | Capsule | 100mg | Ad-din Pharmaceuticals Ltd. | 3.0 |
| Locopain TR | Capsule | 100mg | Asiatic Laboratories Ltd. | 3.0 |
| Miclofen TR | Capsule | 100mg | Millat Pharmaceuticals Ltd. | 3.03 |
| Moov SR | Capsule | 100mg | Astra Biopharmaceuticals Ltd. | 2.5 |
| Movonac TR | Capsule | 100mg | Sharif Pharmaceuticals Ltd. | 3.01 |
| Nasida | Capsule | 100mg | Delta Pharma Limited | 3.0 |
| Nasida SR | Capsule | 100mg | Delta Pharma Limited | 3.0 |
| Neofenac SR | Capsule | 100mg | Modern Pharmaceuticals Ltd. | 3.0 |
| Niro TR | Capsule | 100mg | Everest Pharmaceuticals Ltd. | 2.5 |
| Nodinac SR | Capsule | 100mg | Novus Pharmaceuticals Ltd. | 3.0 |
| Orfenac TR | Capsule | 100mg | Orion Pharma Ltd. | 3.01 |
| Orgafen TR | Capsule | 100mg | Organic Health Care | 3.01 |
| Pain Zero TR | Capsule | 100mg | Reliance Pharmaceuticals Ltd. | 3.0 |
| Panfre SR | Capsule | 100mg | Pacific Pharmaceuticals Ltd. | 3.0 |
| Penac TR | Capsule | 100mg | APC Pharma Limited | 3.0 |
| Penac TR | Capsule | 100mg | APC Pharma Limited | 3.0 |
| Proflam SR | Capsule | 100mg | Novo Healthcare and Pharma Ltd. | 4.0 |
| Proladin TR | Capsule | 100mg | Alco Pharma Limited | 3.01 |
| Renac TR | Capsule | 100mg | Reman Drug Laboratories Ltd. | 3.0 |
| Ronac TR | Capsule | 100mg | General Pharmaceuticals Ltd. | 3.02 |
| Rotafen SR | Capsule | 100mg | Salton Pharmaceuticals Ltd. | 3.01 |
| S-Fenac TR | Capsule | 100mg | Seema Pharmaceuticals Ltd. | 3.0 |
| Sifen TR | Capsule | 100mg | Silva Pharmaceuticals Ltd. | 4.0 |
| Tenac TR | Capsule | 100mg | Team Pharmaceuticals Ltd. | 3.0 |
| Tolfenac-SR | Capsule | 100mg | Globex Pharmaceuticals Ltd. | 3.0 |
| Velofen TR | Capsule | 100mg | Leon Pharmaceuticals Ltd. | 3.02 |
| Volcan TR | Capsule | 100mg | Biopharma Ltd. | 3.02 |
| Volfast TR | Capsule | 100mg | S. N. Pharmaceuticals Ltd. | 3.0 |
| Volfast TR | Capsule | 100mg | S. N. Pharmaceuticals Ltd. | 3.0 |
| Volmax SR | Capsule | 100mg | Eskayef Pharmaceuticals Ltd. | 3.0 |
| Voltex SR | Capsule | 100mg | Allied Pharmaceuticals Ltd. | 0.0 |
| Voltid SR | Capsule | 100mg | Pharmasia Ltd. | 3.02 |
| Vurdon SR | Capsule | 100mg | NIPRO JMI Pharma Limited | 3.01 |