Residon 4
Form: Tablet
Strength: 4mg
Generic Name: Risperidone
Company: Healthcare Pharmaceuticals Ltd.
MRP:৳ 9.0 (Strip=10)
Per Piece: ৳ 0.90
Is Antibiotic: No
Indications
It is used to treat the following conditions:
- Acute and chronic psychosis
- Mania
- Schizophrenia
Pharmacology
It is a selective monoaminergic antagonist that primarily targets serotoninergic 5-HT2 and dopaminergic D2 receptors. It also interacts with alpha1 adrenergic receptors and, to a lesser extent, with H1 histamine and alpha2 adrenergic receptors. Unlike many other drugs, it does not affect cholinergic receptors. As a strong D2 antagonist, it improves the positive symptoms of schizophrenia while causing less motor activity depression. By balancing central serotonin and dopamine antagonism, it reduces the risk of side effects and helps manage both negative and emotional symptoms of schizophrenia.
Dosage & Administration
Psychoses:
Start with 2 mg on the first day (split into 1-2 doses), then 4 mg on the second day (split into 1-2 doses). The typical dose is 4-6 mg daily, but doses above 10 mg per day should only be used if the benefit is considered greater than the risk (maximum dose is 16 mg per day).
For elderly patients or those with liver or kidney problems, start with 1 mg daily, increasing by 1-2 mg twice daily as needed.
Children under 15 should not use this medication.
Mania:
Start with 2 mg once daily, increasing by 1 mg daily if needed. The typical dose range is 1-6 mg daily.
Elderly patients or those with liver or kidney problems should start with 1 mg daily in two doses, increasing by 1-2 mg twice daily.
Schizophrenia:
Initially, take 1 mg twice a day, increasing by 1 mg every two days until 3 mg twice a day is reached by the third day. Dosage adjustments should happen no more frequently than once a week, with small changes of 1-2 mg at a time.
Interaction
It may reduce the effects of levodopa and dopamine agonists. Long-term use with Carbamazepine decreases its levels in the blood, and using it with Clozapine may also lower its clearance. It can also increase the effectiveness of certain blood pressure medications.
Contraindications
It should not be used by people who are allergic to it.
Side Effects
Common side effects include:
- Insomnia
- Agitation
- Anxiety
- Headaches
- Drowsiness
- Difficulty concentrating
- Fatigue
- Blurred vision
- Constipation
- Nausea and vomiting
- Stomach upset
- Abdominal pain
- Increased prolactin levels
- Urine incontinence
- Fast heart rate
- High blood pressure
- Swelling
- Rash
- Cold-like symptoms
- Stroke
- Low white blood cell count and low platelet count
Pregnancy & Lactation
Although no direct harm to reproduction was found in animal studies, some indirect effects related to prolactin and the central nervous system were observed. No birth defects were seen in any studies. The safety of using it during human pregnancy is not established. It is known to pass into animal and human breast milk, so women using it should avoid breastfeeding.
Precautions & Warnings
Special care should be taken if the person has heart problems, is elderly, has liver or kidney problems, epilepsy, Parkinson’s disease, or is pregnant. If symptoms of a movement disorder (tardive dyskinesia) occur, discontinue use.
Overdose Effects
No specific details available.
Therapeutic Class
It belongs to the class of atypical neuroleptic drugs.
Storage Conditions
Store below 30°C, away from light, and keep out of reach of children.
Similar Brands of Risperidone (Tablet – 4mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Frenia 4 | Tablet | 4mg | Incepta Pharmaceuticals Ltd. | 8.0 |
| Resco 4 | Tablet | 4mg | Drug International Ltd. | 5.0 |
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| Risdon 4 | Tablet | 4mg | Unimed Unihealth Pharmaceuticals Ltd. | 9.0 |
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| Sizodon MD 4 | Tablet | 4mg | Sun Pharmaceutical (Bangladesh) Ltd. | 9.5 |
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