Secnid DS
Form: Tablet
Strength: 1gm
Generic Name: Secnidazole
Company: Square Pharmaceuticals Ltd.
MRP:৳ 20.0 (Strip=2)
Per Piece: ৳ 10.00
Is Antibiotic: No
Indications
Secnid DS is used for treating intestinal amoebiasis, hepatic amoebiasis, urethritis and vaginitis caused by Trichomonas vaginalis, and giardiasis.
Pharmacology
Secnid DS is quickly absorbed when taken by mouth, with the highest blood level reached 3 hours after taking a 2 gm dose. The body eliminates Secnid DS mainly through urine, with about half of the dose leaving the body in 5 days. Secnid DS has the longest half-life of second-generation nitroimidazoles, which allows Secnid DS to maintain therapeutic blood levels for up to 72 hours after a single dose.
Dosage & Administration
Acute Intestinal Amoebiasis:
Adults: 2 gm as a single dose, preferably before a meal.
Children: 30 mg/kg as a single dose, preferably before a meal.
Asymptomatic Amoebiasis (minute and cystic form):
Adults: 2 gm once a day for 3 days, preferably before a meal.
Children: 30 mg/kg once a day for 3 days, preferably before a meal.
Hepatic Amoebiasis:
Pus removal should be done along with treatment.
Adults: 1.50 gm/day in single or divided doses, before meals, for 5 days.
Children: 30 mg/kg/day, in single or divided doses, before meals, for 5 days.
Giardiasis:
Adults: 2 gm as a single dose, preferably before a meal.
Children: 35-50 mg/kg as a single dose, preferably before a meal.
Trichomoniasis:
Adults: 2 gm as a single dose, preferably before a meal. The partner should also take the same treatment at the same time.
Interaction
Secnid DS should not be taken with disulfiram, as this may cause confusion and paranoia. When used with warfarin, monitoring is necessary because Secnid DS may increase the effects of anticoagulants and raise the risk of bleeding.
Contraindications
Secnid DS is not recommended for patients who are allergic to imidazole derivatives.
Side Effects
Secnid DS is generally well tolerated, with few serious side effects. However, some people may experience:
Common side effects: Stomach issues like nausea, pain, metallic taste, and mouth irritation.
Occasional side effects: Skin reactions like hives, and mild decrease in white blood cells that goes away once the treatment stops.
Rare side effects: Dizziness, coordination problems, numbness, or nerve damage.
Pregnancy & Lactation
Secnid DS may be used during pregnancy after the first trimester. Secnid DS should not be used during the first trimester or while breastfeeding, as Secnid DS passes into the placenta and breast milk.
Precautions & Warnings
Secnid DS is important not to drink alcohol while using this medicine due to the risk of a severe reaction. Secnid DS should also be avoided by patients with a history of blood disorders.
Overdose Effects
Not available.
Therapeutic Class
Secnid DS belongs to the class of amoebicides and anti-diarrhoeal antiprotozoal medicines.
Storage Conditions
Store in a cool, dry place, away from heat.
Similar Brands of Secnidazole (Tablet – 1gm)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| D-Zole 1gm | Tablet | 1gm | Drug International Ltd. | 17.0 |
| Pronil DS | Tablet | 1gm | The ACME Laboratories Ltd. | 16.11 |
| Secnidal DS | Tablet | 1gm | Sanofi Bangladesh Ltd. | 25.46 |
| Secnizol DS | Tablet | 1gm | Incepta Pharmaceuticals Ltd. | 16.0 |
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